DSPP Scholar Training at the University of Michigan School of Dentistry

摘要 颅面出生缺陷，例如，唇裂和腭裂是最常见的先天性 人类的畸形类似地，影响颅面区域的获得性疾病（例如，头颈 癌症）通过治疗方式（例如，手术以及化疗和放疗）或事故（例如， 交通、火器、烟花）经常对面部造成显著的功能、结构和美学损伤， 嘴巴和头盖骨这些疾病的治疗往往是复杂的，涉及协调工作， 诊所和中心的多学科颅面团队为患者提供全面护理。 尽管最近在治疗选择方面取得了进展，但缺乏控制肿瘤的分子机制的知识， 颅面发育和再生仍然是发展更复杂的 治疗或更有效地预防这些疾病。 这个NIDCR牙科专业和博士课程的目标是帮助确保一个多样化的游泳池，以及- 训练有素的科学家可满足国家的生物医学，行为和临床研究需求。我们 我们相信，这一目标是可以实现的方案，包括有效的招聘，先进的 科学的临床训练，一流的导师，优秀的训练环境。我们利用我们 现有且非常成功的口腔健康科学博士课程和成熟且经过认可的临床 牙科学院的专业课程，为专家提供先进的科学和 临床训练具体来说，这个7年的计划提供博士培训与必修和选修课程， 研究轮换，论文研究，职业和领导力发展，再加上临床 支持学者科学和职业规划的专业培训。我们建议支持现有的两个 学者，谁目前正在追求综合牙科专业和博士培训，直到他们过渡到 在其专业培训的第二年，通过其他供资机制。到那时我们将接纳两名 新的学者，谁将根据强有力的学术记录，研究成就， 致力于研究密集型学术生涯，重点是颅面疾病和障碍， 支持他们如上所述。我们将特别努力招募来自不同国家和地区的学者， 代表性不足的背景。 密歇根大学和牙科学院在研究生教育方面有着悠久的传统， “以学生为中心，以教师为主导”。我们在研究生培养的整体观不仅为学者做好准备， 学术牙科的专业挑战，但也为他们提供技能和经验， 成为独立思考者和终身学习者。这使他们能够发展成为临床大师 有着公认的独立研究职业。我们的目标是教育一个多样化和独特的资格 这将加速我们预防和治疗颅面疾病和障碍的可能性。

ABSTRACT Craniofacial birth defects, e.g., cleft lip and cleft palate, are among the most common congenital malformations in humans. Similarly, acquired diseases affecting the craniofacial region (e.g., head and neck cancer) through treatment modalities (e.g., surgery and chemo- and radiation therapy) or accidents (e.g., traffic, firearms, fireworks) often cause significant functional, structural, and esthetic damage to the face, mouth, and cranium. The treatment of these conditions often is complex and involves the coordinated work of the multidisciplinary craniofacial teams at clinics and centers providing comprehensive care for patients. Despite recent advances in treatment options, the lack of knowledge in molecular mechanisms controlling craniofacial development and regeneration remains a major obstacle in development of more sophisticated therapies or more effective prevention of these conditions. The goal of this NIDCR Dental Specialty and PhD Program is to help ensure that a diverse pool of well- trained scientists is available to address the nation’s biomedical, behavioral, and clinical research needs. We are confident that this goal is achievable through programs that incorporate effective recruitment, advanced scientific and clinical training, superb mentors, and an outstanding training environment. We leverage our existing and highly successful Oral Health Sciences PhD program and the well-established, accredited clinical specialty programs at the School of Dentistry to provide a pipeline of experts with advanced scientific and clinical training. Specifically, this 7-year program offers PhD training with required and elective courses, research rotations, dissertation research and career and leadership development, coupled with clinical specialty training that supports scholars’ scientific and career plans. We propose to support our existing two scholars, who are currently pursuing the integrated dental specialty and PhD training, until they transition to other funding mechanisms during the second year of their specialty training. At that point, we will admit two new scholars, who will be selected based on strong academic records, research accomplishments, and commitment to a research-intensive academic career with a focus on craniofacial diseases and disorders and support them as outlined above. We will make a special effort to recruit scholars from diverse and underrepresented backgrounds. The University of Michigan and the School of Dentistry have a long tradition in graduate education, which is both “student-centered and faculty led”. Our holistic view in graduate training not only prepares scholars for professional challenges of the academic dentistry, but also furnishes them with skills and experiences to become critical independent thinkers and life-long learners. This allows them to develop as master clinicians with recognized independent research careers. Our goal is to educate a diverse and uniquely qualified workforce that will accelerate our possibilities to prevent and treat craniofacial diseases and disorders.