Pulmonary Biostatistics Core

项目总结/摘要 芯e 核心将为三个项目中的每一个项目的严重哮喘研究者提供统计支持的所有方面， 包括实验设计、分析和解释。核心人员将与PPG研究者互动 在研究的所有阶段，包括研究问题和假设的制定，实验设计， 数据管理，数据分析，结果解释，科学手稿和赠款的准备， 传播成果，评估逐步取得的成功和实现整个项目的障碍 目标.具体目标是：（1）与项目研究者合作，确保所有临床和 转化研究和实验经过适当设计，以及（2）为项目研究人员提供支持 在统计分析和报告数据的实验和临床研究。这些目标将是 由Yi Zhao，PhD（核心总监）和James Slaven，MS组成的团队完成， 支持和专业知识。在IU，没有可比较的肺数据分析核心，尽管有 计算生物学和生物信息学的补充计划。

PROJECT SUMMARY/ABSTRACT Core E The Core will provide severe asthma investigators from each of the three Projects all facets of statistical support, including experimental design, analysis, and interpretation. Core personnel will interact with PPG investigators in all stages of research, including the formulation of research questions and hypotheses, experimental design, data management, data analysis, result interpretation, preparation of scientific manuscripts and grants, dissemination of results, and the assessment of stepwise success and barriers to meeting overall project objectives. Specific aims are: (1) to collaborate with project investigators to ensure that all clinical and translational studies and experiments are properly designed, and (2) to provide support to project investigators in the statistical analysis and reporting of data from experiments and clinical studies. These aims will be accomplished by a team consisting of Yi Zhao, PhD (core director) and James Slaven, MS providing biostatistical support and expertise. There is no comparable core for pulmonary data analysis at IU, though there are complementary programs for Computational Biology and Bioinformatics.