Administrative Core

我们建议扩大现有的心理健康研究网络（MHRN），以包括14个研究中心 嵌入到大型卫生系统中，为16个州的2500多万患者提供服务。现有MHRN基础设施 将得到加强，以支持下一代基于实践的网络，包括： ·增加患者、卫生系统领导人和其他利益相关者对网络治理的参与 研究重点的选择 ·一个扩展的公共开源软件工具和其他技术资源库 ·开展可行性试点项目和快速回应利益攸关方询问的更正式程序 ·扩大与外部利益攸关方和研究伙伴的联系 这个整体应用程序要求支持一个管理核心，一个方法核心，两个签名研究 项目和两个试点研究项目。行政核心，由格雷戈里·西蒙和贝琳达领导 Operskalski，将包括一个组织单位，负责治理，战略规划，财政 管理和合规;外联和外部合作股，负责沟通， 资源共享，促进新的合作，并支持可行性试点项目;和一个新兴的 问题股确定和解决内部和外部利益攸关方新出现的问题。的 组织股将维持和加强治理、业务、财政管理和 合规资源在8年的MHRN运营中证明是成功的。在每个站点，核心资源将 研究中心首席研究员（负责监督本地数据基础设施活动， 卫生系统参与）、一名或多名程序员/分析师（负责数据基础设施质量 控制、常规描述性分析和关于新出现问题的分析），以及一个或多个项目 经理（负责本地财务管理和法规遵从）。拟议新订 资金周期，患者和家庭利益相关者将加入网络指导委员会和外部 咨询委员会将参与网络战略规划和评估。外展和外部 协作股将维持和加强通信工具、资源共享机制、保健 系统参与流程和外部调查员参与流程在8年内被证明是成功的 MHRN的运作。接收和响应可行性或试点数据请求的结构化流程 (from无论是基于MHRN还是外部调查员）将包括一个透明的过程， 查询和分配给小型试点项目的具体资源。一个结构化的过程， 回应卫生系统和外部利益相关者的询问将包括技术援助，以结束- 用户，并将从MHRN的大型图书馆的描述性分析，标准查询， 表型

We propose to expand the existing Mental Health Research Network (MHRN) to include 14 research centers embedded in large health systems serving over 25 million patients in 16 states. Existing MHRN infrastructure will be enhanced to support a next-generation practice-based network, including: • Increased engagement of patients, health system leaders, and other stakeholders in network governance and selection of research priorities • An expanded public, open-source library of software tools and other technical resources • More formal processes for conducting feasibility pilot projects and rapid response to stakeholder queries • Expanded outreach to external stakeholders and research partners This overall application requests support for an Administrative Core, a Methods core, two Signature research projects and two Pilot research projects. The Administrative Core, led by Gregory Simon and Belinda Operskalski, will include an Organizational Unit responsible for governance, strategic planning, fiscal management, and compliance; an Outreach and External Collaboration Unit responsible for communications, resource sharing, promoting new collaborations, and supporting feasibility pilot projects; and an Emerging Issues Unit to identify and address emerging questions for internal and external stakeholders. The Organizational Unit will maintain and enhance the governance, operational, fiscal management, and compliance resources proven successful in 8 years of MHRN operations. At each site, core resources will support effort by a site lead investigator (responsible for supervising local data infrastructure activities and health system engagement), one or more programmer/analysts (responsible for data infrastructure quality control, routine descriptive analyses, and analyses regarding emerging issues), and one or more project managers (responsible for local financial management and regulatory compliance). In the proposed new funding cycle, patient and family stakeholders will join the network Steering Committee and an External Advisory Committee will participate in network strategic planning and evaluation. The Outreach and External Collaboration unit will maintain and enhance the communications tools, resource sharing mechanisms, health system engagement processes, and external investigator engagement processes proven successful in 8 years of MHRN operation. A structured process for receiving and responding to requests for feasibility or pilot data (from either MHRN-based or external investigators) will include a transparent process for timely response to queries and specific resources allocated to small pilot projects. A structured process for receiving and responding to queries from health system and external stakeholders will include technical assistance to end- users and will draw from MHRN's large library of descriptive analyses, standard queries, and computable phenotypes.