Administrative Core

摘要：行政核心(AC)将支持该中心的项目主任 转译病毒肿瘤学(CTVO)在其第二阶段操作期间通过提供整体 计划和协调初级校长选拔小组的指导和研究 调查人员(PJI)。管理委员会将负责管理中心的日常运作 中心，组织咨询委员会会议，促进JPI特权访问研究 核心设施，评估新的试点和研究项目，促进跨学科 互动。这将确保初级专业人员有一个适当的职业发展 有兴趣利用他们最重要的研究成果来开发新的预防措施 和/或针对病毒相关癌症的治疗方式。有三个主要因素 这使得CTVO具有极强的竞争力和独特性：1)接触到独特的少数族裔患者 不成比例地受到病毒诱发癌症影响的人群；2)经历了基本的 致力于病毒癌症研究的研究和临床科学家 积极担任CTVO的导师和顾问；以及3)最先进的研究核心 设施。AC是专门为促进这些关键组件而设计的，通过 目标1：提供科学的领导和行政结构 协调各参与机构关于病毒和癌症的专题研究，包括 来自内部和外部顾问的同行审查，以及CTVO与其他计划的集成 致力于研究、病人护理、教学和社区参与。目标2：支持 通过指导和培训培养具有高度竞争力的初级首席调查员 CTVO及其学术部门内的职业发展计划。目标3：推广 研究核心设施的开发、可持续性和有效利用，新颖的科学 技术和资源，同时灌输对性别、经济和 种族包容性，以及在所有活动中的公平。参与机构包括路易斯安那州 国立大学健康科学中心(LSUHSC)，新奥尔良； LSUHSC、什里夫波特和杜兰大学医学中心(TUMC) 该地区的大多数患者护理、研究和科学培训。这些机构 支持最先进的核心设施、肿瘤登记、电子病历、临床试验 单位和生物信息学。我们利用了这些宝贵的机构资源，并拥有 精选优秀的基础研究和临床导师来创造这一高度激励和 为Cobre支持的JPI候选人提供竞争研究环境。

Abstract: The Administrative Core (AC) will support the Program Director of the Center for Translational Viral Oncology (CTVO) during its Phase 2 operation by providing the overall planning and coordination of the mentoring and research for the selected group of Junior Principle Investigators (PJIs). The AC will be responsible for managing the day-to-day operations of the Center, organizing advisory committee meetings, facilitating JPIs privileged access to research core facilities, evaluating new pilots and research projects, and promoting interdisciplinary interactions. This will ensure an appropriate career development for JPIs who have a strong interest in utilizing their most important research findings for the development of new preventive and/or therapeutic modalities against virus-associated cancers. There are three major factors which make the CTVO highly competitive and unique: 1) Access to a unique minority patient population that is disproportionally affected by virus-induced cancers; 2) Experienced basic research and clinical scientists who are dedicated to the study of viral cancers and are highly motivated to serve as mentors and advisors in CTVO; and 3) State-of-the-art Research Core Facilities. The AC is designed specifically to facilitate each of these crucial components through the following specific aims: Aim 1: Provide scientific leadership and administrative structure for coordinating thematic research on viruses and cancer across participating institutions, including peer review from internal and external advisors, and for integration of CTVO with other programs dedicated to research, patient care, teaching, and community engagement. Aim 2: Support the development of highly competitive Principal Junior Investigators (JPIs) through mentoring and career development plans within the CTVO and their Academic Departments. Aim 3: Promote the development, sustainability, and effective utilization of research core facilities, novel scientific techniques and resources while instilling an awareness and sensitivity to gender, economic and ethnic inclusiveness, and equity in all activities. The participating institutions include Louisiana State University Health Sciences Center (LSUHSC), New Orleans; LSUHSC, Baton Rouge; LSUHSC, Shreveport; and Tulane University Medical Center (TUMC), which are responsible for the majority of patient care, research, and scientific training in the region. These institutions support state-of-the-art core facilities, tumor registries, electronic medical records, clinical trial units and bioinformatics. We have engaged these valuable institutional resources and have selected outstanding basic research and clinical mentors to create this highly motivating and competitive research environment for COBRE-supported JPI candidates.