Siyakhula: Growing HIV/TB Research Knowledge for Growing Healthy Kids in Eswatini

项目概要/摘要 与斯威士兰大学、斯威士兰卫生部（包括国家艾滋病毒和结核病防治中心）合作， 项目）和斯坦福大学贝勒医学院将进行艾滋病毒/艾滋病研究方面的培训 方法，重点是儿科和结核病（TB）共病，同时考虑到迫在眉睫的威胁， 气候变化影响儿童健康。其他主要合作伙伴包括德克萨斯大学公共卫生学院 （UTHealth SPH）将在公共卫生硕士和博士阶段支持和指导长期学员 问题研究我们现有的艾滋病毒/结核病合作培训计划（Siyakhula）培训i）三名博士候选人， 成为专注于儿科（婴儿， 儿童、青少年）人口，以及ii）两个国内公共卫生受训人员队列， 儿童健康研究。培训利用了一种新颖的斯威士兰-美国双重指导战略 确保美国长期Siyakhula学者进行的研究的保留，成功和相关性。 长期的Siyakhula学者在UTHealth SPH注册，以获得博士学位或博士学位，并在 斯威士兰在国内从事Siyakhula学者和导师。我们采用“反馈教学”的方法， 长期受训人员参加设在斯威士兰的培训论坛，以发展教学技能， 与国内学者建立伙伴关系。我们的首要目标是加强临床研究能力， 斯威士兰同时培养高质量的研究人员，他们将成功地过渡到 独立，获得独立的资金，并领导国家努力结束艾滋病毒/结核病的流行， 现在考虑到气候变化对健康的影响。 气候变化是我们这个时代的危机。然而，对卫生从业人员和未来科学家的培训 在气候变化议程中几乎缺失;特别是在儿童健康和资源有限的环境中 预计影响最大的地方。我们的创新补充课程i）突出了 儿童健康与气候变化的相互联系，ii）寻求培训当地科学家，临床医生和公众 在一个新兴的非洲研究培训计划中的卫生专业人员，iii）支持当地研究者驱动的 研究确定对Emaswati影响最大的气候变化杠杆，iv）建立监测机制， 核心气候指标，以及iv）承诺带来可衡量的变化，将气候变化作为关键 斯威士兰人类健康的驱动力。我们的合作方法是由当地的研究重点，确保 将气候变化和健康纳入国家研究战略，以产生可持续的影响。

Program Summary/Abstract In collaboration with the University of Eswatini, the Eswatini Ministry of Health (including national HIV and TB programs), and Stanford Unversity, Baylor College of Medicine (BCM) will conduct training in HIV/AIDS research methods with a focus on pediatrics and Tuberculosis (TB) co-morbidity while considering the imminent threat of climate change on children's health. Other key partners include The University of Texas School of Public Health (UTHealth SPH) who will support and mentor long-term trainees during Public Health Masters and Doctoral level studies. Our existing collaborative HIV/TB training program (Siyakhula) trains i) three doctoral candidates to become Independent Investigators in clinical and translational research focusing on HIV/TB in pediatric (infants, children, adolescents) populations, and ii) two in-country cohorts of public health trainees to become Associate Investigators in child health research. The training capitalizes on a novel Eswatini-US dual mentoring strategy to ensure retention, success, and relevance of research conducted by US-based long-term Siyakhula Scholars. Long-term Siyakhula Scholars enroll in UTHealth SPH to earn a PhD or DrPH and conduct thesis activities in Eswatini engaging in-country Siyakhula Scholars and mentors. We employ a "teach-back" approach in which the long-term trainees participate in Eswatini-based training forums to develop teaching skills and strengthen partnerships with in-country scholars. Our overarching goal is to strengthen clinical research capacity in Eswatini while simultaneously producing high-quality researchers who will successfully transition to independence, obtain independent funding and lead national efforts to end the HIV/TB epidemic while now considering the impact of climate change on health. Climate change is the crisis of our time. However, training of health practitioners and tomorrow's scientists has virtually missing from the climate change agenda; particularly for child health and resource constrained setting where the impact is predicted to be greatest. Our innovative supplemental curriculum i) highlights the interconnectedness of child health and climate change, ii) seeks to train local scientists, clinicians, and public health professionals within a burgeoning African research training program, iii) supports local investigator driven research to identify climate change levers that are most impactful for Emaswati, iv) establishes monitoring of core climate metrics, and iv) promises to bring about measurable change regarding climate change as a key driver of human health in Eswatini. Our collaborative approach is driven by local research priorities ensuring integration of climate change and health within the national research strategy to provide sustainable impact.