Penn State Clinical and Translational Science Institute

项目摘要摘要--总体 宾夕法尼亚州立大学临床和转化科学研究所(CTSI)成立于2007年，旨在加快影响 关于健康的生物医学研究。宾夕法尼亚州立大学有近10亿美元的研究支出，其学院 医疗(COM)和宾夕法尼亚州立卫生系统为中部以农村为主的地区约200万人提供服务 爸。宾夕法尼亚州立大学是该州授予土地的大学，是一所具有浓厚跨学科文化的研究机构 团队科学和卫生系统致力于我们地区的人民和社区。我们已经开发出一种 不断扩大的外展网络和伙伴关系，以更好地了解社区的需求，消除障碍 预防和治疗，并测试新的方法，以解决生命周期和翻译过程中的健康问题 频谱。作为一个学习型组织，我们实行持续评估和数据驱动决策，以 实现持续的质量改进。我们的愿景是成为宾夕法尼亚州立大学CTS的基石 推进农村社区卫生服务的带头人。我们愿景的一个关键组成部分是跨学科的团队合作和广泛的 利益相关者的参与是成功的关键。我们的具体目标是： 目标1.通过吸引研究人员、供应商和社区合作伙伴来催化CTS。我们将与 并在宾夕法尼亚州立大学内外建立独特的合作伙伴关系。我们将利用大量的资源 收集与健康有关的数据，为解决健康问题以及社会和环境影响的新方法提供信息； 特别是当它们与我们的农村人口有关时。我们将把农村社区参与和 通过社区活动、咨询服务、劳动力培训和试点项目进行协作。 目标2.通过创新和以研究人员为中心的研究基础设施促进CTS 加快协议开发和研究完成，同时确保科学严谨和 再现性。CTSI为开展CTS研究和临床提供广泛的研究支持和服务 符合我们所服务社区需求的试验。我们将致力于建立一个学术临床 在COM的信息学研究部，促进与复杂的信息学能力的整合 穿过宾夕法尼亚州立大学。这些努力将赋予整个大学的科学家权力。 目标3.通过与其他CTSA中心和 财团。我们是CTSA(临床和翻译科学奖)联盟的积极成员。我们 将增加我们的互动，重点放在与农村社区密切相关的中心合作上。 目标4.教育新一代卫生专业人员和CTS学者，并使他们能够 开展资助的、创新的和跨学科的研究。该研究所将是培训的焦点。 在宾夕法尼亚州立大学，CTSA拥有多样化且不断扩大的CTS学者和专业人员队伍 财团和我们新的合作伙伴关系。

PROJECT SUMMARY ABSTRACT - OVERALL The Penn State Clinical and Translational Science Institute (CTSI) was formed in 2007 to accelerate the impact of biomedical research on health. Penn State has almost $1 billion in research expenditures, and its College of Medicine (CoM) and Penn State Health system serve about 2.0 million people in largely rural regions of central PA. Penn State is the state's land-grant university, a research institution with a strong culture of interdisciplinary team science and a health system committed to the people and communities in our area. We have developed a growing outreach network and partnerships to better understand the communities' needs, address barriers to prevention and treatment, and test novel approaches to health concerns across the lifespan and translational spectrum. As a learning organization, we practice continuous evaluation and data-driven decision-making to achieve continuous quality improvement. Our vision is to be the cornerstone of CTS throughout Penn State and a leader in advancing rural CTS. A key component of our vision is that interdisciplinary teamwork and broad engagement of stakeholders is critical to success. Our specific aims are: Aim 1. Catalyze CTS by engaging researchers, providers and community partners. We will engage researchers and establish unique partnerships across and beyond Penn State. We will capitalize on vast sources of health-relevant data to inform novel approaches to health concerns and social and environmental implications, particularly as they relate to our rural population. We will integrate rural community engagement and collaboration through community activities, consultation services, workforce training, and pilot projects. Aim 2. Promote CTS through innovation and investigator-centered research infrastructure that accelerates protocol development and study completion while ensuring scientific rigor and reproducibility. CTSI provides expansive research support and services to conduct CTS research and clinical trials that meet the needs of the communities we serve. We will pursue the establishment of an academic Clinical Informatics Research Division at the CoM and promote integration with the sophisticated informatics capabilities across Penn State. These efforts will empower scientists across the University. Aim 3. Effectively share resources and expertise through collaboration with other CTSA Hubs and the Consortium. We are active members of the CTSA (Clinical and Translational Science Award) Consortium. We will increase our interactions, focusing on Hub collaborations germane to rural communities. Aim 4. Educate a new generation of health professionals and CTS scholars, and empower them to conduct funded, innovative and interdisciplinary research. The Institute will be the focal point for the training of a diverse and expanding CTS workforce of scholars and professionals across Penn State, the CTSA Consortium and our new partnerships.