North Carolina Translational and Clinical Sciences Institute (NC TraCS)

北卡罗来纳州转化与临床科学研究所 (NC TraCS)

• 批准号: 10621596
• 负责人: John Bernard Buse
• 金额: $ 1004.21万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-28 至 2030-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10621596
• 关键词: Acceleration; Address; Attention; Automobile Driving; Basic Science; Breathing; Clinical; Clinical Research; Clinical Sciences; Clinical Trials Design; Clinical and Translational Science Awards; Communities; Country; Data Science; Development; Discipline; Dissemination and Implementation; Diverse Workforce; Economics; Emergency Situation; Engineering; Ensure; Environment; Evaluation; Event; Fostering; Future; Goals; Harm Reduction; Health; Health Personnel; Health Policy; Healthcare Systems; Home; Human; Informatics; Infrastructure; Institution; Intervention; Laboratories; Lead; Leadership; Learning; Methods; NIH Program Announcements; North Carolina; Outcome; Participant; Patient Recruitments; Patients; Persons; Policies; Population; Population Heterogeneity; Prevention strategy; Process; Public Health; Readiness; Reduce health disparities; Research; Research Infrastructure; Research Institute; Research Personnel; Research Support; Resources; Rural Population; Services; Social Justice; Testing; Time; Training; Translating; Translational Research; Translations; Trust; United States National Institutes of Health; Universities; Veterinary Medicine; Veterinary Schools; Vision; Workforce Development; career; clinical care; computer science; design; diagnostic strategy; empowerment; evidence base; flexibility; health disparity; health equity; health equity promotion; health inequalities; implementation strategy; improved; innovation; multidisciplinary; novel; pandemic disease; programs; recruit; research to practice; rural underserved; social health determinants; translational goal; treatment strategy; vision science

Project Summary The North Carolina Translational and Clinical Sciences Institute (TraCS) is a dynamic regional network of universities, research institutes, healthcare providers, and >250 community collaborators across our state. Based at UNC Chapel Hill, TraCS has strategically fostered partnerships with NC A&T, the largest HBCU in the U.S., which brings expertise in health equity research, workforce development, engineering, and data science, and NC State, with a nationally ranked school of veterinary medicine and additional expertise in engineering and computer science. Over the next seven years, we will catalyze development, testing, implementation, and dissemination of translational science and research to improve human health, with an explicit focus on advancing health equity by completing our Overall Aims. Aim 1: Perform and support research that advances the science of translation with the goal of clearing barriers to rapid translation of research towards implementation of best evidence to our patients and their communities. Aim 2: Maximize the informativeness of translational research, to drive its impact to improve clinical benefits and reduce harms with particular attention to populations impacted by health inequities. Aim 3: Train and maintain a diverse, expert, multidisciplinary translational research workforce at all professional levels, prepared to meet the challenges of current and future health crises. Aim 4: Implement evidence-based strategies to improve human health using our learning health care system as our laboratory. We have intensified our efforts in health equity as well as dissemination and implementation, recognizing that these are the critical barriers to effective translation of innovation to health. We will capitalize on (i) the substantial resources of our learning health care system and (ii) the collective expertise of TraCS, honed over 14 years of supporting world-class translational research, to integrate the principles of social justice in all our services and trainings and to realize our vision of “A healthier North Carolina through innovation”. We will innovate inclusive methods and processes, engender trust, and recruit research participants who reflect the diversity of our state. We will implement our advances to ensure benefits for our participants, their communities and patients everywhere. With broad stakeholder engagement and rigorous evaluation of our efforts, we will maximize the relevance of our research to those we serve. TraCS will lead and support efforts across the CTSA consortium to create a more efficient, inclusive research environment to mitigate health disparities.

项目摘要 北卡罗来纳州翻译和临床科学研究所(TraCS)是一个充满活力的区域网络， 全州的大学、研究机构、医疗保健提供者和250个社区合作者。 总部设在北卡罗来纳教堂山的TraCS从战略上促进了与NC A&T的合作伙伴关系，NC A&T是美国最大的HBCU 美国，它带来了卫生公平研究、劳动力发展、工程和数据方面的专业知识 理工学院和北卡罗来纳州立大学，拥有全国一流的兽医学校和其他专业知识 工程学和计算机科学。在接下来的七年里，我们将推动开发、测试、 实施和传播翻译科学和研究，以改善人类健康， 明确关注通过完成我们的总体目标来促进健康公平。目标1：执行和支持 促进翻译科学进步的研究，其目的是清除快速翻译的障碍 向我们的患者及其社区提供最佳证据的研究。目标2：最大限度地 转化性研究的信息性，以推动其影响，从而提高临床效益并减少危害 特别关注受健康不平等影响的人群。目标3：培养和保持一支多元化的、专家的、 所有专业级别的多学科翻译研究团队，准备迎接 当前和未来的健康危机。目标4：实施循证战略以改善人类健康 我们的学习型医疗保健系统作为我们的实验室。 我们加强了在卫生公平以及传播和执行方面的努力，认识到 这些都是有效地将创新转化为健康的关键障碍。我们将利用(I) 我们学习的医疗保健系统的大量资源和(Ii)TraCS的集体专业知识，经过磨练 14年来支持世界级的翻译研究，将社会正义的原则融入我们所有的 服务和培训，并实现我们的愿景“通过创新更健康的北卡罗来纳州”。我们会 创新包容性方法和流程，建立信任，招募反映以下情况的研究参与者 我们州的多样性。我们将实施我们的预付款，以确保我们的参与者及其社区的利益 到处都是病人。通过广泛的利益相关者参与和对我们努力的严格评估，我们将 最大限度地提高我们的研究与我们所服务的人的相关性。TRACS将领导和支持世界各地的努力 CTSA联盟创建一个更高效、更具包容性的研究环境，以缓解健康差距。