Developing and testing the Opioid Rapid Response System

摘要 这一第二阶段的SBIR将开发和展示阿片类药物快速反应系统(ORRS)对 改善对阿片类药物过量的反应。阿片类药物过量在生命和支出方面造成了巨大的代价。 纳洛酮已被开发用于对抗过量；然而，这些事件的性质需要快速的 响应，这种情况对人口稀少的农村地区的应急人员以及 人口密集的城市社区。现在存在的应用程序有可能通过链接来消除计时问题 通过911系统对事件进行非专业公民响应。其中一款名为PulsePoint的应用程序已经在4100个版本中到位 而另外两个潜在的合作伙伴，OpiSafe和Brave， 专注于吸毒过量，并拥有不断扩大的客户基础。其他社区则简单地将纳洛酮作为 越广泛越好。如果没有有效的解决方案，无论是纳洛酮分销还是应用程序都无法实现他们的目标 招募和培训许多既能救命又能用纳洛酮的市民急救员 对自己有能力做到这一点充满信心。到目前为止，还没有基于证据的计划来实现这些目标。 该项目旨在制定创新和有效的征聘和培训战略，以填补这一空白。 ORRS是基于一个试点项目，该项目演示了非专业公民响应者可以利用PulsePoint应用程序 应对服药过量事件。在第一阶段，我们开发了一种基于身份理论的有效招聘方案 利用个人诉求(个人身份诉求)和他人诉求(集体诉求)并加以管理 通过多种方式。我们还开发了一个ORRS在线培训的原型，并演示了可用性 并通过在印第安纳州五个县的研究来验证其可行性。在第二阶段，ORRS的招聘将细化为 提高社交媒体的表现，培训平台将得到加强，重点放在 心肺复苏术和减少耻辱以及加强参与，并将在#年开展一项国家区域合作研究。 社区。将评估招募和训练对心理和行为结果的影响。 该项目很有希望通过PulsePoint、OpiSafe和Brave快速广泛地传播 社区和公共卫生部门的技术合作网络。这个项目有潜力 开发社区应对类似公共卫生事件的模式。

Abstract This Phase II SBIR will develop and demonstrate the efficacy of the Opioid Rapid Response System (ORRS) to improve responses to opioid overdoses. Opioid overdoses exact a tremendous cost in lives and expenditures. Naloxone has been developed to counteract overdoses; however, the nature of these events requires a rapid response, a situation that challenges emergency responders in both lightly populated rural areas as well as densely populated urban communities. Apps now exist with the potential to obviate timing concerns by linking lay citizen responders to events through the 911 system. One such app, PulsePoint, is already in place in 4,100 communities throughout the U.S. for cardiac events, while two other potential partners, OpiSafe and Brave, focus on overdoses and have expanding customer bases. Other communities simply distribute naloxone as widely as possible. Neither naloxone distribution nor the apps can accomplish their goals without effectively recruiting and training many citizen responders who are both able to administer life-saving naloxone and confident in their ability to do so. To date, there are no evidence-based programs to accomplish these goals. This project is designed to develop innovative and effective recruitment and training strategies to fill this gap. ORRS was based on a pilot project demonstrating that lay citizen responders could utilize the PulsePoint app to respond to overdose events. In Phase I, we developed an effective recruitment protocol based on identity theory that uses appeals to individuals (personal identity appeals) and others (communal appeals) and administered it through multi-modalities. We also developed a prototype of ORRS online training and demonstrated usability and feasibility through a study in five Indiana counties. In Phase II, ORRS recruitment will be refined to improve the performance of the social media component, the training platform will be enhanced to focus on CPR and stigma reduction as well as enhanced engagement, and a national RCT will be conducted in 8 communities. Recruitment and training effects on psychological and behavioral outcomes will be evaluated. The project has great promise for rapid and wide dissemination through the PulsePoint, OpiSafe, and Brave Technology Coop networks of communities as well as public health departments. The project has the potential to develop a model for community responses to similar public health events.