Core 02: Biostatistics, Epidemiology & Research Design Core

项目概要：生物统计学、流行病学和 研究设计（BERD）核心 路易斯安那州生物统计学，流行病学和研究设计（BERD）核心的总体目标 临床和转化科学中心（LA CaTS）旨在确保所有临床和转化研究 在LA CaTS范围内进行的研究符合研究设计和分析的最高科学标准。 在前两个资助期内，BERD成功地利用了现有的教师专业知识， 主要的合作机构，并实施了一个综合的BERD支持网络，现在可以 所有参与的LA CaTS机构的研究人员。对外经贸关系部现在提供服务和咨询， 包括我们的路线图和功勋学者在内的全州调查人员以及其他调查人员 寻求将他们的研究扩展到翻译工作。洛杉矶猫队的领导层，以及他们各自的 机构，提供了大量的资源，使BERD核心，以扩大我们的生物统计能力， 额外的流行病学专业知识，并提供独特的生物统计方法的熟练程度。为 为LA CaTS调查人员提供全面的BERD资源，该核心是内部最受欢迎的服务之一。 洛杉矶猫中心在即将到来的周期，我们将通过以下目标扩大我们的支持网络：目标1。 提供一个易于访问的，用户友好的生物统计学，流行病学和研究设计专业知识资源 对于临床和转化研究人员，特别是那些专注于服务不足和 在全国范围内代表性不足的人口。BERD将利用其专业知识提供新的 资源，如高维和定量成像数据，以确保所有LA CaTS研究人员 随时获得所需的统计援助。目标2.参与未来临床医学教育， 翻译研究人员通过提供客观的，良好的实践，通过研究进行科学调查的培训， 设计方法和定量统计做法。BERD核心将与 专业发展（PD）核心和社区参与和推广（CEO）核心，以教育 研究人员、公民科学家和社区利益攸关方对统计概念的认识。目标3。扩大 了解和使用统计分析，以确保研究能够解决差距问题，促进卫生公平 都是经过充分设计并使用严格的统计技术。与飞行员密切合作 项目计划（PPP）核心，BERD将确保每个项目都有健全的统计严谨性，包括 有足够的能力进行亚组分析，并解决有关健康差距的问题。因此，BERD 核心努力与全州的临床和转化研究人员合作，以推进科学研究。 通过合理的统计技术发现。

Project Summary: Biostatistics, Epidemiology & Research Design (BERD) CORE The overall goal of the Biostatistics, Epidemiology, and Research Design (BERD) Core of the Louisiana Clinical and Translational Science Center (LA CaTS) is to ensure that all clinical and translational research conducted within the purview of LA CaTS meets the highest scientific standards for study design and analysis. During the previous two funding periods, the BERD has successfully leveraged existing faculty expertise from the primary collaborating institutions and implemented an integrated BERD support network that is now available to investigators at all participating LA CaTS institutions. The BERD now provide services and consultation to investigators across the state including our Roadmap and Meritorious Scholars, and to other investigators seeking to expand their research toward translational efforts. The LA CATS leadership, and their respective institutions, provided considerable resources enabling the BERD Core to expand our biostatistics capacity, add additional epidemiology expertise, and provide unique proficiency in biostatistical approaches. As the comprehensive BERD resource for LA CaTS investigators, this core is one of the most requested services within the LA CaTS Center. For the upcoming cycle, we will expand our support network by the following Aims: Aim 1. Provide an easily accessible, user-friendly resource of biostatistics, epidemiology, and research design expertise for clinical and translational researchers, particularly those with projects focused on underserved and underrepresented populations throughout the state. The BERD will leverage its expertise to provide new resources such as high dimensional and quantitative imaging data, to ensure all LA CaTS researchers have ready access to statistical assistance as required. Aim 2. Participate in the education of future clinical and translational researchers by providing training in objective, good-practice, scientific investigation through study- design methodologies and quantitative statistical practices. The BERD Core will work closely with the Professional Development (PD) Core and the Community Engagement and Outreach (CEO) Core to educate researchers, citizen scientists, and community stakeholders on statistical concepts. Aim 3. Expand the knowledge and use of statistical analyses to ensure studies that address disparities and promote health equity are adequately designed and use statistically rigorous techniques. Coordinating closely with the Pilot Projects Program (PPP) Core, the BERD will ensure that every project has sound statistical rigor, including adequate power for subgroup analyses, and to address issues regarding health disparities. Thus, the BERD Core strives to collaborate with clinical and translational researchers across the state to advance scientific discoveries through sound statistical techniques.