Hawaii IDeA Center for Pediatric and Adolescent Clinical Trials 2 (HIPACT 2)

摘要 夏威夷IDEA儿童和青少年临床试验中心第二个周期的主要目标2 （HIPACT 2）是利用HIPACT前四年的成功， 儿童健康结果的环境影响IDEA国家儿科临床试验网络（ECHO ISPCTN）网站。HIPACT前四年推出ECHO ISPCTN临床试验，聘请新初级 ECHO ISPCTN的研究人员努力在HIPACT的合作伙伴建立儿科临床试验能力 机构职能体系作为一个相对较小的ECHO ISPCTN临床试验机构，历史上很少有儿科参与临床试验， 试验，HIPACT成功地激发和从事新的初级教师在整个专业的频谱 发展活动。HIPACT的初步成功激发了学术和社区的动力 努力充分参与HIPACT 2的规划，包括新承诺的合作伙伴。我们建立 一种通过儿科和母胎医学系参与HIPACT 2的机制， 夏威夷儿科研究（HIPR）学者计划。此外，我们还将奋进为 ECHO ISPCTN活动的目标是增加参与HIPACT 2的初级教师的数量。与 总体目标是改善农村和农村地区不同多民族人口的健康和福祉， 夏威夷服务不足的地区，包括夏威夷土著社区和太平洋移民人口 岛民和亚洲人，HIPACT 2将利用与夏威夷太平洋健康中心建立的HIPACT合作伙伴关系 (HPH)Kapiolani妇女和儿童医疗中心（KMCWC）和Waitheit Coast Comprehensive Health 中心（WCCHC）。目标1：积极促进和参与 ECHO ISPCTN儿科临床试验;目标2：提供临床试验，使农村和服务不足的人群受益 婴儿、儿童和青少年，其中许多是夏威夷土著人、太平洋岛民和亚洲人;目标3： 参与ECHO ISPCTN多中心临床试验研究的“科学”;目标4：指导 初级教师通过夏威夷儿科研究（HIPR）学者计划。总之，HIPACT 2将作为 作为ECHO ISPCTN在第二个五年融资周期中的热切合作伙伴， 参与和成就，机构支持和新承诺的合作伙伴。它将丰富机会 教师研究培训和教育，参与合作多中心临床试验研究，以及 让农村和服务不足的社区参与进来，以改善夏威夷和全国各地的健康状况。

ABSTRACT The principal objective of this second cycle of Hawaii IDeA Center for Pediatric and Adolescent Clinical Trials2 (HIPACT2) is to capitalize on the success of the first fouryears of HIPACT as a productive and engaged Environmental Influences of Child Health Outcomes IDeA States Pediatric Clinical Trials Network (ECHO ISPCTN) site. The first four years of HIPACT launched ECHO ISPCTN clinical trials, engaged new junior investigators in ECHO ISPCTN endeavors and built pediatric clinical trials capacity at HIPACT's partner institutions. As a relatively small ECHO ISPCTN site with a historical paucity of pediatric involvement in clinical trials, HIPACT successfully inspired and engaged new junior faculty across the spectrum of professional development activities. The initial success of HIPACT spirited the momentum for academic and community efforts to participate fully in the planning of HIPACT2 including newly committed partners. We have established a mechanism to participate in HIPACT2 by engaging pediatric and maternal-fetal medicine faculty through the Hawaii Pediatric Research (HIPR) Scholars Program. Moreover, we will endeavor to feed into the pipeline of ECHO ISPCTN activities with the goal of increasing the number of junior faculty involved in HIPACT2. With the overarching goal to improve the health and wellbeing of the diverse multiethnicpopulations in rural and underserved areas of Hawaii including indigenous Hawaiian communities, and immigrant populations of Pacific Islanders and Asians, HIPACT2will capitalize on established HIPACT partnerships with Hawaii Pacific Health (HPH) Kapiolani Medical Center for Women and Children (KMCWC), and Waianae Coast Comprehensive Health Center (WCCHC). The following Specific Aims are proposed: Aim 1: To actively contribute to and participate in ECHO ISPCTN pediatric clinical trials; Aim 2: To provide access to clinical trials to benefit rural and underserved infants, children, and adolescents, many of who are Native Hawaiians, Pacific Islanders, and Asians; Aim 3: To participate in the “science” of ECHO ISPCTN multicenter clinical trials research; Aim 4: To mentor a cadre of junior faculty via the Hawaii Pediatric Research (HIPR) Scholars Program. Taken together, HIPACT2 will act as an eager partner in ECHO ISPCTN in this second five-year cycle of funding with a strong historical track record of engagement and achievement, institutional support, and newly committed partners. It will enrich opportunities for faculty research training and education, participation in collaborative multicenter clinical trial research, and engage rural and underserved communities to improve health outcomes in Hawaii and across the nation.