Core-002

综合系统免疫学核心（ISIC/Core 2） 迫切需要一种能够在感染前或感染前后诱导保护性免疫的艾滋病毒疫苗。 性初次登场的时间我们的计划旨在实现这一目标，并建立综合系统免疫学核心 （国际标准工业分类）通过建立一个用于生成高内容数据的联合、统一资源，支持整个使命， 数据储存、分析和向科学界传播。具体而言，综合系统 Immunology Core专注于提供单细胞免疫反应测量，微生物组分析 和数据策展到项目和NHP核心。作为数据生成和管理中心，ISIC 在结果的整合和解释方面也发挥着核心作用，托管定量和微生物组 技术工作组，以简化这些程序。核心将与行政核心合作 确保结果的严谨性和可重复性，并有效实施系统生物学方法， 实现这一艾滋病毒防治赠款的总体目标。

ABSTRACT – Integrated Systems Immunology Core (ISIC/Core 2) There is a critical and urgent need for a HIV vaccine that can induce protective immunity prior to or around the time of sexual debut. Our Program seeks to achieve this goal, and the Integrated Systems Immunology Core (ISIC) supports the overall mission by establishing a joint, unified resources for high-content data generation, data warehousing, analysis and dissemination to the scientific community. Specifically, the Integrated Systems Immunology Core focusses on providing single cell Immune-response measurements, microbiome analysis and data curation to both Projects and the NHP Core. As a data generation and management hub, the ISIC also plays a central role in integration and interpretation of results, hosting both quantitative and microbiome technical working groups to streamline these processes. The Core will collaborate with the Administrative Core to ensure rigor and reproducibility of results and effective implementation of systems biology approaches to achieve the overall goals of this HIVRAD grant.