Einstein-Mount Sinai Diabetes Research Center

总结/摘要： 由于高死亡率（全世界感染者的2%以上）， 个人发展急性后COVID-19综合征，国家糖尿病研究所， 消化和肾脏疾病（NIDDK）组织了一个由糖尿病研究组成的工作组， 中心（DRC）和糖尿病转化研究中心（CDTR）探索研究 应对COVID-19相关问题的方向， 新陈代谢.与会者普遍认为，两项相关的努力在当前和未来都具有重要意义 价值，并在春季NIDDK理事会会议上得到认可。此申请为A 补充代表了我们对NIDDK资金的正式请求，以支持第二年的一项 一项新的研究计划，将利用NIDDK资助的DRC的建立 CDTR基础设施。 在这一框架内，有两个首要目标。当前的目标是培养 COVID-19代谢研究利用现有技术和优势， 与国家DRC和CDTR计划一起存在。长期目标是开发一个工作流程 用于扩大糖尿病/肥胖和代谢性疾病的国家研究合作， 基础、临床、转化、社区和健康领域的疾病研究社区 差距水平。为达致这些目标，我们建议继续推行第二年的 为我们在2001年支持的三个活跃奖项提供资金。

SUMMARY/ABSTRACT: Due to the high mortality (>2% of infected individuals world-wide) with ~25% of infected individuals developing post-acute COVID-19 syndromes, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) organized a taskforce composed of Diabetes Research Centers (DRCs) and Centers for Diabetes Translational Research (CDTRs) to explore research directions that should be harnessed to address the issues associated with COVID-19 and metabolism. Two related efforts were broadly agreed upon to be of important current and future value and were endorsed at the Spring NIDDK Council meeting. This application for a Supplement represents our formal request for NIDDK funds to support the second year of a novel research program that will take advantage of the established of the NIDDK funded DRC and CDTR infrastructures. Within this framework, there are two overarching goals. The immediate goal is to foster COVID-19 metabolism research which leverages the existing technologies and strengths that exist with the national DRC and CDTR programs. The long-term goal is to develop a work flow for expanding national research collaborations across the diabetes/obesity and metabolic disease research communities at the basic, clinical, translational, community and health disparity levels. To accomplish these objectives, we propose to continue the second year of funding for the three active awards that we have support in year 01.