Scanning ocular Aberration Measurement(SAM) System

描述（由申请人提供）：目的：开发一种扫描眼像差测量（SAM）系统，解决当前波前传感器的五个问题。目前的系统没有：1）在调节期间测量像差; 2）根据眼像差的严重程度允许可变密度采样; 3）监测作为环境照明和调节的函数的瞳孔大小和位置。此外，4）它们将波前像差的拟合限制为Zernike展开，而不评估引起的平滑误差的影响或提供替代的波前表示。最后，5）高成本限制了市场渗透。 具体目标：通过开发光学试验板和原型软件、将软件与试验板集成以及评估组合系统性能来证明可行性。 研究方法：对采用与微孔径阵列耦合的可移动微透镜阵列、瞳孔监测系统和改进的分析软件的透视SAM系统进行试验和测试。 健康相关性：一种具有改进的实用性的具有成本效益的仪器，能够处理更广泛的患者，加快了经验证的实验室技术向临床护理的转移。 技术创新：通过扫描与微孔径阵列耦合的微透镜阵列、透视设计、根据环境照明和调节的瞳孔位置监测、改进的软件实用程序、更低的成本，根据需要进行可变空间采样。

DESCRIPTION (provided by applicant): Objective: Develop a Scanning ocular Aberration Measurement (SAM) system that solves five problems of current wavefront sensors. Current systems do not: 1) measure aberrations during accommodation; 2) allow variable density sampling depending on the severity of the ocular aberration; 3) monitor pupil size and location as a function of ambient illumination and accommodation. Further, 4) they limit the fitting of wavefront aberration to a Zernike expansion without evaluating the impact of the induced smoothing error or providing an alternative wavefront representation. Finally, 5) high cost limits market penetration. Specific Aims: Demonstrate feasibility by developing an optical breadboard and prototype software, integrating the software with the breadboard, and evaluating combined system performance. Methods: Bread-boarding and testing a see-through SAM system employing a movable micro-lenslet array coupled with a micro-aperture array, pupil monitoring system and improved analysis software. Health Relatedness: A cost effective instrument with improved utility capable of handling a broader range of patients quickens the transfer of proven laboratory technology to clinical care. Technological innovation: Variable spatial sampling dependent on need by scanning a micro-lenslet array coupled with a micro-aperture array, see-through design, pupil location monitoring as function of ambient illumination and accommodation, improved software utilities, lower cost.