Mechanisms of metastasis in urological cancers

癌症扩散到其他器官是90%癌症死亡的原因。该提案旨在确定泌尿系统肿瘤（前列腺和膀胱）如何在体内扩散。癌细胞和动物模型是研究的一个组成部分，与人类癌症标本中获得的数据一起，提供了一种全面、有力的方法来确定涉及肿瘤扩散的关键途径。这对于设计治疗和或防止肿瘤扩散的新疗法至关重要。

The spread of cancer to other organs is responsible for 90% of cancer deaths. This proposal seeks to determine how urological tumours (prostate and bladder) spread around the body. Cancer cell and animal models are an integral component of the research, and together with data obtained in human cancer specimens provide a comprehensive, powerful approach to identify key pathways involved in tumour spread. This is critical for the design of new therapies to treat and-or prevent tumour spread.