Training in Genetics

描述：(申请者提供)本申请寻求CWRU遗传学研究生培训计划的再次支持，该计划的目标是将学生培养成杰出的独立学者和研究人员，将遗传学作为研究生物和生物医学问题的主要工具。该计划理念中的决定性因素是培训实验室所追求的广泛的生物体、生物系统和方法。无论学生的研究重点是人类、分子还是发育遗传学；无论是果蝇、线虫、酵母、小鼠还是人类；无论是使用克隆DNA、培养细胞、模式生物还是人类家庭，每个学生都应该对其他生物或专业所追求的一系列方法和主题有广泛的理解和欣赏。实现这一目标的培训是通过五个主要机制实现的：高级课程、每周期刊俱乐部、特邀演讲者研讨会项目、学生研究报告和原创研究。CWRU遗传学研究生培训计划为学生提供了一系列独特的机会。培训实验室设在几个系，包括遗传学、分子生物学、神经科学、儿科、医学和麻醉学。该计划在人类遗传学、分子遗传学、基因组学、基因表达、发育遗传学、染色体结构和功能、基因组图谱和组织、数量遗传学以及人类疾病的分子和遗传学基础方面提供了广泛的新设施和研究计划，从而为从酵母到线虫和果蝇再到小鼠和人类的生物遗传学的所有方面提供了综合培训的机会。该培训计划由遗传学系管理，该系包括基础科学和临床教职员工。学生可以通过CWRU的多项目生物医学培训项目或直接申请遗传学项目来录取。所有一年级学生进行一系列不同的研究轮换，并在第一年结束时选择一个实验室，由遗传学项目的研究导师(培训师)指导。该计划由一个由主任和教员培训员组成的指导委员会管理，每个人都负责计划的具体方面。这一分子、发育和人类遗传学的综合培训计划反映了我们对遗传学多样性的承诺，将其作为所有生物学和医学的统一主题。

DESCRIPTION: (provided by applicant) This application seeks renewed support of the Genetics Graduate Training Program at CWRU, the goal of which is to train students to be outstanding independent scholars and investigators using genetics as a major tool to study biological and biomedical problems. The defining element in the philosophy of the program is the broad range of organisms, biological systems, and approaches being pursued in the training laboratories. Whether a student's research focus is in human, molecular, or developmental genetics; whether in Drosophila, C. elegans, yeast, mouse, or human; whether using cloned DNA, cultured cells, model organisms or human families, each student is expected to develop a broad understanding of and appreciation for the range of approaches and topics being pursued in other organisms or specialties. Training towards this goal is achieved through five primary mechanisms: advanced coursework, a weekly journal club, an invited speaker seminar program, student research presentations, and original research. The CWRU Genetics Graduate Training Program offers a unique range of opportunities for students. Training laboratories are located in several departments, including Genetics, Molecular Biology, Neuroscience, Pediatrics, Medicine and Anesthesiology. The program offers extensive new facilities and research programs in human genetics, molecular genetics, genomics, gene expression, developmental genetics, chromosome structure and function, genome mapping and organization, quantitative genetics and the molecular and genetic basis of human disease, thereby providing an opportunity for integrated training in all aspects of genetics in organisms ranging from yeast to C. elegans and Drosophila to mouse and humans. The training program is administered by the Department of Genetics, which includes both basic science and clinical faculty. Students are admitted either through the multi-program Biomedical Sciences Training Program at CWRU or by direct application to the Genetics Program. All first-year students perform a series of diverse research rotations and select a laboratory with a research mentor (trainer) in the Genetics program at the end of the first year. The program is administered by a Steering Committee consisting of the Director and faculty trainers, each with responsibilities for specific aspects of the program. This integrated training program in molecular, developmental, and human genetics reflects our commitment to the diversity of genetics as a unifying theme across all of biology and medicine.