Training in Recovery of Function After CNS Injury

描述(申请人提供)：这是一份继续支持机构培训补助金的申请，用于中枢神经系统损伤后的可塑性和功能恢复。请求支助四名博士后和四名博士后实习生，以及一名短期(即3个月)研究员。该培训计划的长期目标是培养能够确定中枢神经系统损伤后功能恢复的潜在机制的科学家和医生，并确定和实施促进这种恢复的方法。这个应用程序汇集了华盛顿特区两个机构(乔治城大学和国家康复医院)的基础科学家和临床科学家。这些博士前实习生将从乔治敦大学神经科学跨学科项目(一个基础广泛的、非院系的研究生项目，最终获得神经科学博士学位)获得博士学位。针对中枢神经系统损伤后的功能恢复，制定了一套全面的博士后和博士后培训计划。项目主任和培训人员是长期的导师和研究人员，项目主任在中枢神经系统损伤后的功能恢复方面具有临床和基础科学经验。培训环境促进了教师和学员的协作、多学科研究努力。许多教师都有以前和正在进行的合作；学生们被鼓励在具有互补研究兴趣的教师之间寻求共同指导。除了正式的课程作业和实验室研究轮换外，博士后和博士后学员还会参加持续的系列研讨会、联合神经学、神经外科、神经科学大轮回、国家专业会议、特别强调中枢神经系统可塑性、功能再生和恢复的期刊俱乐部、密集的实验室研究以及撰写和审阅手稿的培训，并在医学神经科学课程中提供辅导教学机会。受训人员还有许多机会与来访的科学家互动，并在地方和国家会议上介绍他们的研究成果。一个由来自8个不同科室的21名教员组成的经验丰富、资金雄厚的小组将参加培训，他们具有良好的培训记录、广泛的研究兴趣和与中枢神经系统损伤后的可塑性和功能恢复有关的专业知识。

DESCRIPTION (provided by applicant): This is an application for continued support of an Institutional Training Grant in CNS Plasticity and Recovery of Function after CNS Injury. The request is for support of four predoctoral and four postdoctoral trainees, and one short term (i.e. 3 month) fellow. The long-range goal of this training program is to prepare scientists and physicians who will be in a position to define the mechanisms underlying recovery of function following central nervous system injury and to identify and implement methods to enhance that recovery. This application brings together basic scientists and clinician scientists at two institutions in Washington, D.C. (Georgetown University and the National Rehabilitation Hospital). The predoctoral trainees will receive their Ph.D. from the Interdisciplinary Program in Neurosciences at Georgetown (a broad-based, non-departmental graduate program leading to a Ph.D. in Neuroscience). A comprehensive training program aimed at recovery of function after CNS injury has been developed for pre- and postdoctoral training. The Program Director and Training Faculty are long-time mentors and researchers and the Program Director has both clinical and basic science experience in recovery of function after CNS injury. The training environment fosters collaborative, multidisciplinary research efforts of both faculty and trainees. Many of the faculty have previous and ongoing collaborations; students are encouraged to seek co-mentorship between faculty with complementary research interests. In addition to formal coursework and laboratory research rotation, pre- and postdoctoral trainees participate in an ongoing seminar series, joint Neurology, Neurosurgery, Neuroscience grand rounds, national professional meetings, a journal club with special emphasis on CNS plasticity, regeneration and recovery of function, intensive laboratory research and training in writing and reviewing manuscripts, grantsmanship, and are provided mentored teaching opportunities in the Medical Neuroscience course. Trainees are also given many opportunities to interact with visiting scientists and to present their research at local and national meetings. An experienced and well-funded group of 21 faculty from 8 different departments with strong training records, a wide range of research interests and expertise relevant to plasticity and recovery of function after CNS injury will participate in training.