National Capital Area Rehibiliation Research Network

描述（由申请人提供）：这个国家首都地区康复研究网络（NCARRN）汇集了基础神经科学（乔治城大学）、生物医学工程（国家康复医院、天主教大学和乔治城大学）和临床研究和护理（国家康复医院）的优秀项目，以建立一个全国公认的脊髓损伤跨学科研究项目，基于动物和人类研究。在这种情况下，pi提供了一个集中的研究基础设施，这将提高医学康复研究者识别和理解功能恢复背后的神经机制的能力，并设计和实施治疗策略，以增强这些机制，提高脊髓和其他中枢神经系统损伤患者的生活质量。Barbara S. Bregman博士和Joseph Hidler博士担任项目主管。这个国家首都地区康复研究网络在基于活动的中枢神经系统可塑性和功能恢复方面创造了一个独特的国家研究核心资源：基础神经科学，生物医学工程，成像（动物和人类MRI和fMRI）以及脊髓损伤的临床研究和护理。该NCARRN由四个研究核心和一个管理核心组成。行政核心协调休假和试点赠款计划，并通过组织讲习班、课程和专题讨论会向康复社区提供持续的教育和培训。行政核心还协调了一个强大的研究设计和拨款写作发展计划。研究核心是：A)康复机器人：基于活动的康复方法；B)成像技术：动物和人类中枢神经系统可塑性的可视化；C)损伤、可塑性和功能恢复动物模型；D)可塑性的细胞和分子方法。该网络位于华盛顿特区的中心位置，交通便利，为直接大都市地区以外的合作提供了绝佳的焦点。NCARRN在中枢神经系统损伤和康复方面提供了一个杰出的研究基础设施，并汇集了已建立的研究人员，核心资源以及访问康复研究学者的休假和试点资助计划，这些学者准备成为为康复做出贡献的强大的独立研究人员。通过提供核心资源、强有力的指导和广泛互动的机会，该项目将加强医学康复研究，改善脊髓损伤和其他神经系统疾病患者的预后。

DESCRIPTION (provided by applicant): This National Capital Area Rehabilitation Research Network (NCARRN) brings together outstanding programs in basic neuroscience (at Georgetown University), biomedical engineering (at National Rehabilitation Hospital, Catholic University, and Georgetown University) and clinical research and care (at National Rehabilitation Hospital) to establish a nationally recognized interdisciplinary research program in spinal cord injury, based on both animal and human studies. In this capacity, the PIs provide a centralized research infrastructure which will enhance the capability of medical rehabilitation investigators to identify and understand the neural mechanisms underlying functional recovery, and to design and implement therapeutic strategies to enhance these mechanisms to improve the quality of life for individuals with spinal cord and other CNS injuries. Barbara S. Bregman, Ph.D., PT and Joseph Hidler, Ph.D. serve as program directors. This National Capital Area Rehabilitation Research Network creates a unique national resource of research cores in activity based CNS plasticity and recovery of function: basic neuroscience, biomedical engineering, imaging (animal and human MRI and fMRI) and clinical research and care in spinal cord injury. This NCARRN is comprised of four research cores and an administrative core. The administrative core coordinates the sabbatical and pilot-grants programs and provides ongoing education and training to the rehabilitation community through the organization of workshops, courses, and symposia. The administrative core also coordinates a strong research design and grant writing development program. The Research Cores are: A) Rehabilitation Robotics: Activity-based approaches to rehabilitation; B) Imaging Technologies: Visualizing CNS Plasticity in Animals and Humans; C) Animal Models of Injury, Plasticity and Recovery of Function; and D) Cellular and Molecular Approaches of Plasticity. The central location of this network in Washington, DC with its easy access provides an excellent focus for collaborations beyond the immediate metropolitan area. This NCARRN provides an outstanding research infrastructure in CNS Injury and Recovery and brings together established investigators, core resources and a sabbatical and pilot grants program for visiting rehabilitation research scholars who are poised to become strong independent investigators contributing to rehabilitation. By providing core resources, strong mentorship and opportunities for broad interaction, this program will increase strong medical rehabilitation research and improve outcomes for individuals with spinal cord injury and other neurological disorders.