Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis
Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis
批准号:
nhmrc : 1088005
负责人:
A/Pr Allison Abendroth
金额:
$42.14万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31
中文摘要
水痘带状疱疹病毒和单纯疱疹病毒是在大多数人群中引起疾病的甲型疱疹病毒。本提案将探讨这两种密切相关的疱疹病毒的疾病和发病机制的基本问题,重点是这些病毒如何控制宿主功能。特别是,我们将定义这些病毒与自然杀伤(NK)细胞反应之间的相互作用。
英文摘要
Varicella Zoster Virus and Herpes Simplex Virus are alpha-herpesviruses that cause diseases in a majority of the human population. This proposal will explore issues fundamental to disease and pathogenesis of these two closely related herpesviruses, focusing on how these viruses can control host function. In particular, we will define the interactions between these viruses and the natural killer (NK) cell response.
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会议论文
Understanding the role of ongoing viral activity in herpes simplex virus latency
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批准号:nhmrc : 1126599
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项目类别:Project Grants
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资助金额:$67.04万
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财政年份:2017
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负责人:A/Pr Allison Abendroth
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依托单位:
Defining key mechanisms that underpin neuropathogenesis of varicella zoster virus during herpes zoster
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批准号:nhmrc : 1063744
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项目类别:Project Grants
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资助金额:$41.11万
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财政年份:2014
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负责人:A/Pr Allison Abendroth
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依托单位:
Defining a novel mechanism of control of host functions by human cytomegalovirus that enhances viral pathogenesis
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批准号:nhmrc : 1063738
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项目类别:Project Grants
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资助金额:$41.11万
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财政年份:2014
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负责人:A/Pr Allison Abendroth
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依托单位:
The role of varicella zoster virus in modulating cutaneous infection
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批准号:nhmrc : 1010166
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项目类别:Project Grants
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资助金额:$37.07万
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财政年份:2011
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负责人:A/Pr Allison Abendroth
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依托单位:
Human cytomegalovirus encoded control of the latent phase of infection
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批准号:nhmrc : 1006199
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项目类别:Project Grants
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资助金额:$42.67万
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财政年份:2011
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负责人:A/Pr Allison Abendroth
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依托单位:
Neuropathogenesis of varicella zoster virus infection
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批准号:nhmrc : 570998
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项目类别:NHMRC Project Grants
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资助金额:$34.09万
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财政年份:2009
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负责人:A/Pr Allison Abendroth
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依托单位:
Mechanisms of immune modulation by Varicella zoster virus during cutaneous infections
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批准号:nhmrc : 457356
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项目类别:NHMRC Project Grants
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资助金额:$38.04万
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财政年份:2007
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负责人:A/Pr Allison Abendroth
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依托单位:
Immunopathogenesis of varicella zoster virus infection
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批准号:nhmrc : 352341
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项目类别:NHMRC Project Grants
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资助金额:$23.09万
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财政年份:2005
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负责人:A/Pr Allison Abendroth
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依托单位:
Mechanisms of immune modulation by human cytomegalovirus during the latent phase of infection
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批准号:nhmrc : 301942
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项目类别:NHMRC Project Grants
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资助金额:$11.04万
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财政年份:2004
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负责人:A/Pr Allison Abendroth
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依托单位:
Molecular mechanisms of varicella zoster virus interactions with key target cells
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批准号:nhmrc : 211110
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项目类别:NHMRC Project Grants
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资助金额:$28.12万
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财政年份:2002
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负责人:A/Pr Allison Abendroth
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依托单位:
海外基金