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Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis

Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis
水痘带状疱疹病毒和单纯疱疹病毒控制宿主功能增强发病机制
批准号:
nhmrc : 1088005
负责人:
A/Pr Allison Abendroth
金额:
$42.14万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31

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中文摘要
翻译
水痘带状疱疹病毒和单纯疱疹病毒是在大多数人群中引起疾病的甲型疱疹病毒。本提案将探讨这两种密切相关的疱疹病毒的疾病和发病机制的基本问题,重点是这些病毒如何控制宿主功能。特别是,我们将定义这些病毒与自然杀伤(NK)细胞反应之间的相互作用。
英文摘要
Varicella Zoster Virus and Herpes Simplex Virus are alpha-herpesviruses that cause diseases in a majority of the human population. This proposal will explore issues fundamental to disease and pathogenesis of these two closely related herpesviruses, focusing on how these viruses can control host function. In particular, we will define the interactions between these viruses and the natural killer (NK) cell response.
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Understanding the role of ongoing viral activity in herpes simplex virus latency
  • 批准号:
    nhmrc : 1126599
  • 项目类别:
    Project Grants
  • 资助金额:
    $67.04万
  • 财政年份:
    2017
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    A/Pr Allison Abendroth
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Defining key mechanisms that underpin neuropathogenesis of varicella zoster virus during herpes zoster
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    nhmrc : 1063744
  • 项目类别:
    Project Grants
  • 资助金额:
    $41.11万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Allison Abendroth
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Defining a novel mechanism of control of host functions by human cytomegalovirus that enhances viral pathogenesis
  • 批准号:
    nhmrc : 1063738
  • 项目类别:
    Project Grants
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    $41.11万
  • 财政年份:
    2014
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    A/Pr Allison Abendroth
  • 依托单位:
The role of varicella zoster virus in modulating cutaneous infection
  • 批准号:
    nhmrc : 1010166
  • 项目类别:
    Project Grants
  • 资助金额:
    $37.07万
  • 财政年份:
    2011
  • 负责人:
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海外基金