Core A: Administrative Core

核心A：项目总结 管理核心(核心A)对耶鲁大学孢子皮肤癌(YSPORE)的成功至关重要。这个 核心的主要目的是支持和促进皮肤癌的跨学科研究努力，并确定 新的挑战和机遇不断涌现。行政核心是中心协调 YSPORE调查人员的重点，负责监测所有项目和核心的进展情况 转换/临床终点。这些服务包括提供(A)财政管理、(B)文书和 组织支助，(C)内部和外部审查机制，(D)支持加强科学 项目/核心领导之间的互动和协作，(E)监测项目和核心的机制 (F)协调外联工作；(G)建立扩大皮肤癌研究的机制 除了孢子的活动，耶鲁大学内外都是如此。核心A还将负责 确保耶鲁大学孢子在皮肤癌方面的活动与耶鲁癌症中心和 其他耶鲁大学的孢子，目标是避免重叠和重复努力，同时最大限度地发挥协同作用 和资源的使用。孢子调查员之间可能出现的任何冲突将由核心解决 A董事，由执行委员会、外部和内部咨询委员会以及Eric提供意见 如果需要，马里兰州温纳。核心A将与生物统计和生物信息学核心(核心C)密切合作，以确保 将孢子计划产生的数据与耶鲁癌症中心产生的数据进行整合，反之亦然 监督与其他皮肤癌/黑色素瘤孢子网站的数据共享，并在适当的情况下与耶鲁大学共享数据 肺癌中的孢子和耶鲁大学的头颈部孢子。A核心将组织联合科学研究 与孢子研究人员举行进展会议，以确保思想的双向交流和交流 资源。参与该项目的调查人员还将参加一年一度的孢子间研讨会， 由核心A与其他站点的管理核心协作组织。《核心》将由Dr。 Marcus Bosenberg和Harriet Kluger，联席主任是Mario Sznol博士。核心A将对计划进行监督 在执行委员会的投入下完成，对科学和行政职能的投入将是 征求内部和外部咨询委员会的意见。与内部和外部咨询机构举行年度会议 董事会将由Core A组织。Core还将组织正在进行的研究研讨会、外部讲座 调查人员、病人和社区外展。

CORE A: PROJECT SUMMARY The Administrative Core (Core A) is critical to the success of the Yale SPORE in Skin Cancer (YSPORE). The primary purpose of the Core is to support and facilitate transdisciplinary research efforts in skin cancer and identify new challenges and opportunities as they emerge. The Administrative Core serves as the central coordination point for YSPORE investigators, with responsibility for monitoring the progress of all projects and cores toward a translational/clinical endpoint. These services include provision of (a) fiscal management, (b) clerical and organizational support, (c) mechanisms for internal and external review, (d) support for enhancement of scientific interactions and collaborations among the Project/Core leaders, (e) mechanisms to monitor projects and cores for scientific progress, (f) coordination of outreach efforts, and (g) mechanisms to expand research in skin cancer beyond the activities of the SPORE, both within Yale and outside of Yale. Core A will also be responsible for ensuring full integration of activities of the Yale SPORE in Skin Cancer with those of Yale Cancer Center and the other Yale SPOREs, with the goal of avoiding overlap and duplication of efforts while maximizing synergy and use of resources. Any conflicts that might arise between SPORE investigators will be addressed by the Core A Directors, with input from the Executive Committee and the External and Internal Advisory Boards and Eric Winer, MD if needed. Core A will work closely with the Biostatistics and Bioinformatics Core (Core C) to ensure the integration of data generated by the SPORE program into that of Yale Cancer Center and vice versa, and to oversee sharing of data with other skin cancer/melanoma SPORE sites, and when appropriate, with the Yale SPORE in Lung Cancer and the Yale Head and Neck SPORE. Core A will organize joint scientific research in progress meetings held with the SPORE researchers, to ensure bi-directional flow of ideas and sharing of resources. Investigators involved in this program will also participate in the annual inter-SPORE workshops, organized by Core A in collaboration with Administrative Cores at other sites. The Core will be directed by Drs. Marcus Bosenberg and Harriet Kluger and the Co-Director is Dr. Mario Sznol. Program oversight by Core A will be done with input from the Executive Committee, and input for scientific and administrative functions will be sought from the Internal and External Advisory Boards. Annual meetings with the Internal and External Advisory Boards will be organized by Core A. The Core will also organize research in progress seminars, talks by outside investigators, and patient and community outreach.