Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk)

超过三分之一的女性患有心脏病，许多人不知道风险。高血压是一种主要的 高血压是心血管疾病（CVD）的可改变风险因素，美国约47%的成年人患有高血压。在 约85%的病例，高血压的原因不明，只有约50%的患者服用药物达到 血压（BP）控制在推荐水平。限制CVD过早死亡的关键障碍是 对心血管疾病的风险缺乏认识。我们在美国东南部的位置将有助于我们 冲击GA、MS和SC的高血压和肥胖患病率较高。 相关风险在所有人群中并不相等。事实上，黑人高血压的患病率 在美国是世界上最高的。我们的总体目标是改变学术和社区 将性别作为一个生物学变量（SABV）来考虑高血压。要全面完成 通过创造和传播创新的教育内容， 伙伴关系，并加强社区参与在美国东南部。该评分旨在 为女性与男性控制血压的机制提供了新的见解， 从小学延伸到医学院的心血管病SABV教育平台，并提高认识 和教育的心血管疾病和风险的不受控制的高血压的妇女在整个健康跨度， 社区外展这个分数有四个目标。目标1是进行前沿研究， 我们对控制血压以限制心血管风险的性别特异性机制的理解。目标二： 发展一个文化多样性的生物医学科学家的研究渠道，在CVD的SABV领域接受培训。 目标3是建立一个由受过培训的科学家组成的社区外联渠道，以提高对SABV的认识 并促进男性和女性的最佳心血管保健。目标4：增强社区能力 自我监测，并努力找出改善医疗保健服务的障碍。我们建议的结果 SCORE不仅包括科学进步和培养下一代领导人的研究， 生物性别对CVD的发展和进展的影响，但也有一系列的发展， 教育内容，将完全提供给财团。这包括：（1）发展教育 医学插图材料，供各阶段学生/受训者、社区和医生使用，2） 建立SABV指导学院，3）为学生，研究员， 和初级调查员我们工作的影响将是提高对下列风险的认识和认识： 心血管疾病和高血压的妇女在他们的健康跨度和SAVB实验设计的最佳实践。 我们全面的社区外展计划对于接触到非洲大陆的高危人群也至关重要。 美国东南部增加常规心血管健康监测并降低总体CVD负担 对人口和医疗系统的影响。

More than 1 in 3 women are living with heart disease and many are unaware of the risks. Hypertension is a major modifiable risk factor for cardiovascular disease (CVD), and ~47% of adults in the US have hypertension. In ~85% of cases, the cause of hypertension is unknown and only ~50% of patients taking medication achieve blood pressure (BP) control to recommended levels. A critical barrier to limiting premature death from CVD is lack of awareness surrounding the risks of CVD. Our location in the Southeast of the US will contribute to our impact. The prevalence of hypertension and obesity are high in GA, MS, and SC. The prevalence of hypertension and associated risk is not equal among all populations. Indeed, the prevalence of hypertension in Black people in the US is among the highest in the world. Our overall goal is to transform academic and community understanding of sex as a biological variable (SABV) in the consideration of hypertension. We will accomplish this through the creation and dissemination of innovative educational content, the development of strategic partnerships, and enhanced community engagement in the Southeast of the US. This SCORE is designed to provide novel insight into the mechanisms controlling BP in females vs. males, develop a comprehensive educational platform on SABV in CVD extending from grade school to medical school, and increase awareness and education of CVD and the risks of uncontrolled hypertension in women across the health span through community outreach. This SCORE has 4 objectives. Objective 1 is to conduct cutting edge research to advance our understanding of sex-specific mechanisms that control BP to limit cardiovascular risk. Objective 2 is to develop a culturally diverse research pipeline of biomedical scientists trained in the field of SABV in CVD. Objective 3 is to establish a community outreach pipeline of trained scientists to increase awareness of SABV and promote optimal cardiovascular healthcare for men and women. Objective 4 is to empower the community to self-monitor and work to identify barriers to improving access to healthcare. The outcomes of our proposed SCORE include not only advances in science and training of the next generation of leaders in the study of the impact of biological sex on the development and progression of CVD, but also the development of a range of educational content that will be fully available to the Consortium. This will include 1) the development educational materials by medical illustrators for students/trainees at all stages, the community, and physicians, 2) establishing a SABV Mentoring Academy, 3) creating a SABV curriculum and workshop for students, fellows, and junior investigators. The impact of our work will be to increase recognition and awareness of the risks of CVD and hypertension to women across their health span and best practices for SAVB experimental design. Our comprehensive community outreach plan will also be critical to reach a highly at-risk population in the Southeast of the US to increase routine cardiovascular health monitoring and decrease the overall CVD burden on both the population and the healthcare system.