Dental-Biomedical Engineering Scholars Training (D-BEST) Program

项目摘要 哥伦比亚大学是独特的定位，提供先进的双培训的下一代牙科 牙科和生物医学工程的科学家，让他们做好准备，领导日常实践的转变 个性化和精确治疗的发展趋势。通过过去10年的战略投资， 哥伦比亚大学已成为牙医生物医学工程研究培训的场所。学院 牙科医学（CDM）创建了一个新的15，000平方英尺的精密牙科中心， 将传统的牙科实践转变为数字化中心，以真实的时间跟踪临床活动。48个中的每一个 operatories能够跟踪患者、提供者和牙科器械的使用和位置。此外，哥伦比亚 CDM是该国第一批通过以下方式完全整合牙科和医疗电子记录的学校之一 EPIC，提供完整的患者健康记录。此外，生物医学系 工程（DBME），成立于2000年，已迅速上升为排名前10位的毕业生之一 生物医学工程专业，并在每个教师的资金方面领先全国，在 基础领域（生物成像、生物材料、生物力学）以及前沿研究领域（细胞和组织 工程学、神经工程学、合成生物学和深度学习）。我们在这里提出一个新的牙科- 生物医学工程学者培训（D-BEST）计划，汇集了领先的生物医学 哥伦比亚大学的工程研究人员、牙科临床医生和学者。这种独特的双学位 DDS/博士培训计划将整合牙科和生物医学工程研究培训的牙科 四个关键主题领域的科学家：1）干细胞和再生工程，2）颅面成像和 生物力学，3）牙科诊断的大数据和深度学习，以及4）口腔检测和建模 疾病D-BEST的两个轨道是（i）Pre-Doc -牙科（DDS）的8年双学位课程， （ii）博士后-生物医学工程博士后研究培训 美国或外国的牙医。在5年内，我们计划有24个博士预科和7个博士后 每名受训人员的津贴期为3年。除了非常成功的夏季健康 牙科教育计划（SHPEP），我们正在与庞塞健康牙科医学院合作 波多黎各的科学大学，以提高受训人员的多样性，并确保 在D-BEST计划中，来自传统上代表性不足的群体的学员。新的T90/R90培训计划 将提供一个独特的机会，以促进，加强和深化多学科牙科研究。我们长久以来- 在这5年赠款之外，我的长期目标是继续为此开展一个富有成效和可持续的项目 牙科科学家的综合培训，具有扎根于工程和牙科科学的专业知识。是 预计新一代牙科科学家将领导个性化解决方案的创建， 消除该国成年人口腔健康状况持续不佳的现象。 1

PROJECT SUMMARY Columbia University is uniquely positioned to provide advanced dual training of the next generation of dental scientists in dentistry and biomedical engineering, to prepare them to lead the transformation of the daily practice of dentistry towards personalized and precision treatments. Through strategic investment over the last 10 years, Columbia University has become the place for biomedical engineering research training of dentists. The College of Dental Medicine (CDM) has created a new 15,000 sq ft Center for Precision Dentistry that transforms the traditional dental practice into a digitalized hub that tracks clinical activities in real time. Each of the 48 operatories is able to track patients, providers and dental instruments usage and location. In addition, Columbia CDM is one of the first schools in the country to fully integrate dental and medical electronic records through EPIC, which provides an integrated patient’s health record. Moreover, the Department of Biomedical Engineering (DBME), established in 2000, has quickly risen to become one of the top 10 ranked graduate programs in Biomedical Engineering, and leads the nation in funding per faculty, with renowned strength in foundational areas (bioimaging, biomaterials, biomechanics) as well as in frontier research areas (cell and tissue engineering, neuroengineering, synthetic biology and deep learning). We propose here a new Dental- Biomedical Engineering Scholars Training (D-BEST) Program that brings together leading biomedical engineering researchers and dental clinicians and scholars at Columbia University. This unique dual-degree DDS/PhD training program will integrate dental and biomedical engineering research training of dental scientists in four key thematic areas: 1) Stem Cells and Regenerative Engineering, 2) Craniofacial Imaging and Biomechanics, 3) Big Data and Deep Learning for Dental Diagnostics, and 4) Detection and Modeling of Oral Diseases. The two tracks of D-BEST are (i) Pre-Doc – an 8-year dual degree program in dentistry (DDS) and in Biomedical Engineering (PhD), and (ii) Post-Doc – post-doctoral research training in biomedical engineering to US or foreign trained dentists. Over the 5 years, we plan to have 24 pre-doctoral slots and 7 post-doctoral slots with each trainee staying on the grant for 3 years. In addition to the highly successful Summer Health Professions Education Program (SHPEP), we are partnering with the School of Dental Medicine at Ponce Health Sciences University in Puerto Rico to enhance the diversity of the trainee pool and ensure participation of trainees from traditionally under-represented groups in the D-BEST program. This new T90/R90 training program will provide a unique opportunity to promote, enhance, and deepen multidisciplinary dental research. Our long- term goal, above and beyond this 5-year grant, is to continue with a productive and sustainable program for this integrated training of dental scientists, with expertise rooted in both engineering and dental sciences. It is anticipated that this new generation of dental scientists will lead the creation of personalized solutions to eliminate the persistent poor oral health of adults in this country. 1