BIOMOLECULE CHARACTERIZATION AND SEPARATION CORE FACILITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 德克萨斯大学埃尔帕索分校提议继续支持一个多用户研究设施，专门从事生物分子的分离和表征，这是分子生物学的核心设施。该设施维护着离心机、超离心机、伽马和闪烁计数器、带有多个检测器的高效液相色谱仪、毛细管电泳仪、UV/VIS分光计、微孔板阅读器和许多其他共享设备。许多其他资源也可用于记录和分析使用这些仪器收集的实验数据。目前，这个核心还装备用于核酸的合成和放大。由于可能的搬迁和与受影响的用户群体的讨论，这些能力可能会进行重组，以更好地满足用户的需求。这一设施的目的是为最广泛的用户群体提供使用维护良好的最先进设备的途径。存放这些仪器的两个房间中的每一个每月都有100多名个人用户输入超过1000次，代表了15个以上的研究小组。该设施将配备一名全职协调员，负责日常维护、工厂代表安排预防性维护、用户导向和协助以及账户和库存维护。将向核心主任提供部分薪金，以便对这些活动进行持续监督

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Texas at El Paso proposes continuing support for a multi-user research facility specializing in the separation and characterization of biomolecules, the molecular biology core facility. This facility maintains equipment such as centrifuges, ultracentrifuges, gamma and scintillation counters, HPLC with numerous detectors, capillary electrophoresis, UV/vis spectrophotometers, microplate readers and many other items of shared equipment. Numerous other resources are available as well to document and analyze experimental data collected using these instruments. Currently, this core is also equipped for the synthesis and amplification of nucleic acids. These capabilities may be reorganized to better serve the needs of users as a result of possible relocation and discussions with affected user groups. The purpose of this facility is to provide the broadest possible group of users with access to well maintained, state of the art, equipment. Each of two rooms housing these instruments is entered more than 1000 times per month by more than 100 individual users, representing more than 15 research groups. This facility will be staffed by a full-time coordinator who will be responsible for routine maintenance, scheduling preventative maintenance by factory representatives, user orientation and assistance as well as account and inventory maintenance. Partial salary will be provided to the core director for ongoing oversight of these activities