Advancing Child Health through Cellular and Molecular Biology

描述（由申请人提供）：密歇根大学儿童健康研究职业发展奖（CHRCDA）计划题为“通过细胞和分子生物学促进儿童健康”，旨在支持有前途的年轻儿科研究人员的研究职业发展。该研究计划的重点是促进年轻儿科研究人员的研究计划，其工作旨在促进我们对儿童健康中生物系统和疾病过程的理解。该计划特别强调研究的三个基本领域-系统和发育生物学，异常细胞生长和宿主防御。这些领域利用了密歇根大学现有的研究优势和项目。该方案的具体目标是：（a）向初级儿科医生-科学家提供基础设施、技术和机会，以研究影响儿童健康的疾病的基本机制和发病机理;（B）为初级儿科医生-科学家提供一个独特的机会，在细胞和分子生物学以及相关的生物信息学/系统生物学方法方面的创新和最先进的科学专业知识;（c）为初级儿科医生-科学家提供建立成功的独立研究计划所需的研究理解和实验室研究技能;以及（d）招聘有才华的初级儿科医生，特别努力为少数民族和女性候选人提供学术儿科职业。为了实现这些目标，我们聚集了来自不同生物医学研究领域的高级教师，为我们的学员担任研究导师。该方案设立了一个咨询委员会，负责监督该中心学者的甄选工作，并安排了两名征聘干事，协助确定和征聘少数民族和妇女候选人。CHRCDA学者参加细胞和分子生物学的强化培训计划以及旨在确保其持续研究发展的导师计划。该计划为30多名儿科研究人员的培训做出了贡献，他们继续建立成功的研究计划，旨在提高我们对儿童疾病的理解，并开发治疗儿童疾病的新方法。

DESCRIPTION (provided by applicant): The University of Michigan Child Health Research Career Development Award (CHRCDA) program entitled 'Advancing Child Health through Cellular and Molecular Biology" is designed to support the research career development of promising young pediatric investigators. The focus of this research program is to foster the research programs of young pediatric investigators whose work is designed to advance our understanding of biological systems and disease processes in child health. The program places particular emphasis on three fundamental areas of research inquiry-Systems and Developmental Biology, Abnormal Cellular Growth and Host Defenses. These areas take advantage of established research strengths and programs at the University of Michigan. The specific goals of the program are: (a) to provide junior pediatric physician- scientists with the infrastructure, technologies and opportunity to study basic mechanisms and the pathogenesis of diseases that impact children's health; (b) to provide a unique opportunity for junior pediatric physician-scientists to acquire new, innovative and state-of the art scientific expertise in cellular and molecular biology and the associated bioinformatics/systems biology approaches; (c) to provide junior pediatric physician-scientists with the research understanding and bench research skills required to establish a successful independent research program; and (d) to recruit talented junior pediatricians with particular efforts directed towards minority and woman candidates to careers in academic pediatrics. To achieve these goals, we have assembled senior faculty from diverse biomedical research fields to serve as research mentors for our trainees. The program has established an advisory committee to oversee the selection of CHRCDA scholars and the program has put in place two recruitment officers to assist in the identification and recruitment of minority and women candidates. The CHRCDA scholars participate in intensive training programs in cellular and molecular biology as well as a mentorship program designed to ensure their continued research development. This program has contributed to the training of more than 30 pediatric- investigators who have gone on to establish successful research programs designed to improve our understanding of childhood disease as well as develop new therapeutic approaches to treat childhood disease.