Clinical Academic Oncologist Training Program

描述(由申请人提供)：威斯康星大学保罗·卡拉布雷西K12临床肿瘤学奖的目标是培养出成功的、高度合格的临床研究人员，他们致力于与患者相关的肿瘤学研究的学术生涯。这些研究人员将能够领导和管理独立的临床肿瘤学研究项目，并在协作团队环境中与基础、临床和翻译研究人员互动。这项申请描述了一个灵活的职业发展计划，具有肿瘤类型特定的、多学科的方法来进行和设计假说驱动的临床试验。为了实现这一目标，该计划的具体目标是：1)通过提供肿瘤学、生物统计学、伦理学、沟通和监管问题的指导和教学计划，培训内科、外科或放射肿瘤学家和其他合适的临床肿瘤学研究候选人；2)培训研究人员将基础癌症研究成果转化为临床治疗试验所需的技能，以便在临床研究的协作团队研究环境中有效地工作；以及3)通过获得多学科、肿瘤类型特定研究的专业知识和职业生涯发展的指导，培养学术领袖。琼·席勒博士将担任项目负责人。基于核心教学要求的个性化培训计划将与UW K30(临床研究人员预备计划)一起开发。所有学员将由一名临床和实验室导师和项目负责人指导。咨询委员会将监测所有受训人员的进展情况，并评估和监测培训方案的总体效果。华盛顿大学的其他资源将提供给学员，包括华盛顿大学综合癌症中心、麦卡德尔癌症研究所、华盛顿大学GCRC、第一阶段实验治疗计划、第二阶段临床试验联盟、UWCCC生物统计学和生物医学计算资源，以及与东部合作肿瘤学小组的密切联系。自2001年5月该基金招募了第一名实习生以来，已有7人被接纳为临床讲师(其中4人是从威斯康星州大学以外招聘的)。这7人中有4人是女性，7人中有2人是NIH定义的少数民族。7人中有3人仍在训练中。在完成该项目的4人中，有3人担任教职，并积极参与临床肿瘤学研究。这项申请的主要变化包括在临床适当的情况下允许助理教授的学术头衔。

DESCRIPTION (provided by applicant): The goal of the University of Wisconsin Paul Calabresi K12 Clinical Oncology Award is to produce successful, highly qualified clinical investigators who are committed to an academic career in patient related oncology research. These investigators will be capable of leading and managing independent clinical oncology research programs and of interacting with basic, clinical, and translational researchers in collaborative team settings. This application describes a flexible career development program with a tumor-type specific, multi-disciplinary approach to the conduct and design of hypothesis-driven clinical trials. To accomplish this goal, the specific objectives of the program are to: 1) train medical, surgical, or radiotherapy oncologists and other appropriate candidates in clinical oncology research by providing a mentoring and didactic program in oncology, biostatistics, ethics, communication, and regulatory issues; 2) train researchers in the skills necessary to translate basic cancer research results into clinical therapeutic trials, so as to work effectively in a collaborative team research setting for clinical research; and 3) develop academic leaders by acquisition of expertise in a multi-disciplinary, tumor-type specific research and by mentorship in professional career development. Dr. Joan Schiller will serve as the Program Leader. Individualized training programs, based on a core didactic requirement, will be developed in conjunction with the UW K30 (Clinical Investigator Preparatory Program). All trainees will be mentored by a clinical and lab-based mentor and the Program Leader. The Advisory Committee will monitor the progress of all trainees and evaluate and monitor overall effectiveness of the training program. Additional resources of the UW, which will be available to the trainees, include the UW Comprehensive Cancer Center, the McArdle Institute for Cancer Research, the UW GCRC, the Phase I Experimental Therapeutics Program, the Phase II Clinical Trials Consortium, UWCCC Biostatistics and Biomedical Computing resources, and strong ties to the Eastern Cooperative Oncology Group. Since this grant recruited its first trainee in May 2001, 7 individuals have been accepted into the program as clinical instructors (4 of whom were recruited from outside the UW). Four of the 7 are women, and 2 of the 7 are NIH-defined minorities. Three of the 7 are still in training. Of the 4 who have completed the program, 3 have faculty positions and are active in clinical oncology research. Major changes made to this application include allowing the academic title of Assistant Professor, where clinically appropriate.