Metabolic and Neurobiological changes after Continuous Positive Airway Pressure treatment for Obstructive Sleep Apnea

CPAP是阻塞性睡眠呼吸暂停综合征患者的首选治疗方法，因为它被证明能够减少嗜睡和改善血压控制。这项研究将明确确定CPAP是否也能改善心脏代谢健康的指标，如内脏脂肪、胰岛素敏感性、中心血压和动脉僵硬。这项研究的结果将阐明阻塞性睡眠呼吸暂停综合征的更广泛的健康后果，并有助于制定更有针对性的治疗战略。

CPAP is the preferred treatment for patients with OSA because of its well-proven ability to decrease sleepiness and improve blood pressure control. This study will definitively establish if CPAP can also improve markers of cardio-metabolic health, such as visceral fat, insulin sensitivity, central blood pressure and arterial stiffness. The results of the study will shed light on the broader health consequences of OSA and contribute to the development of more targeted treatment strategies.