ADHD IN FETAL DRUG AND ALCOHOL EXPOSURE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 检验产前可卡因暴露针对先前发现的ADHD儿童中受损的相同多巴胺能回路的假设 并确定产前酒精暴露是否会损害这些相同的回路，或者其对注意力的影响是否通过不同的神经通路介导。为了测试可卡因暴露是否是突触后的，因此对哌醋甲酯没有反应。以检查大脑结构异常。测试PNAE与PNCE和特发性ADHD的不同

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To test the hypothesis that prenatal cocaine exposure targets the same dopaminergic circuits previously found to be impaired in children with ADHD and to determine if prenatal alcohol exposure impairs these same circuits or whether its effects on attention are mediated through different neural pathways. To tests if cocaine-exposed is postsynaptic and therefore unresponsive to Methylphenidate. To examine brain structural abnormalities. To tests that PNAE is different than PNCE and idiopathic ADHD