BIOPHYSICAL BASIS OF MUSCLE FUNCTIONAL MRI

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 肌肉功能磁共振成像(MfMRI)是指运动肌肉的信号强度(SI)高于非运动肌肉，被认为是一种检测肌肉对运动的代谢和血流动力学反应的工具。然而，其机制基础仍不清楚。本研究的目的是对mfMRI的生理和生物物理机制提供全面和定量的描述。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Muscle functional magnetic resonance imaging (mfMRI), in which exercising muscles appear with higher signal intensity (SI) than non-exercising muscles, has been proposed as a tool for examining the metabolic and hemodynamic responses of muscles to exercise. However, its mechanistic basis remains unclear. The purpose of this study is to provide a comprehensive and quantitative description of the physiological and biophysical mechanisms underlying mfMRI.