NON-CONTACT CHARACTERIZATION OF RED BLOOD CELL MECHANICAL PROPERTIES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 希尔伯特相位显微镜（HPM）是我们实验室开发的一种新型成像技术，能够以完全非侵入性的方式提供有关纳米和毫秒级红细胞波动的定量信息。我们开发了一个 数学算法，其允许从空间分辨的均方波动中提取物理参数，例如膜弯曲模量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hilbert phase microscopy (HPM) is a novel imaging technique developed in our lab that is capable of providing quantitative information about the red blood cells fluctuations at the nanometer and millisecond level, in a completely non-invasive manner. We developed a mathematical algorithm which allows extracting physical parameters, such as the membrane bending modulus, from the spatially resolved mean squared fluctuations.