TIME-RESOLVED 3D QUANTITATIVE FLOW MRI OF VESSELSWITH PARALLEL IMAGING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 准确了解主要脑血管的血流特征对脑血管异常的诊断具有重要意义。这涉及到血流动力学临界区的评估以及生物力学参数的推导，如壁面剪应力和压力梯度。在这个项目中，采用了一种时间分辨的、使用平行成像的三维相衬磁共振方法来测量心脏周期内多个情况下的三维血流。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Exact knowledge of blood flow characteristics in the major cerebral vessels is of great relevance for diagnosing cerebro-vascular abnormalities. This involves the assessment of hemodynamically critical areas as well as the derivation of biomechanical parameters like wall shear stress and pressure gradients. For this project a time-resolved, three-dimensional phase-contrast MRI method using parallel imaging was implemented to measure blood flow in three-dimensions at multiple instances over the cardiac cycle.