AUTOMATED SPECIMEN HANDLING

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目的重点是开发一个机器人系统，用于将网格加载到样品台中，然后将载物台加载到显微镜中。 自动化方法已经成为快速发展高通量蛋白质晶体学方法的关键组成部分。我们的目标是原型类似的自动化样品处理方法的分子电子显微镜。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project focuses on the development of a robotic system for loading grids into the specimen stage and subsequently loading the stage into the microscope. Automated methods have been a critical component in the rapid development of high throughput methods for protein crystallography. Our objective is to prototype similar automated sample handling methods for molecular electron microscopy.