Clinical & Transitional Research Support

临床和转译研究支持 凯瑟琳·布拉登，医学博士，理查德·W·瑟纳博士，爱德华·I·金斯，医学博士，博士。 修订建议书简介 这是对我们2002年申请时提交的一份提案的修订(优先分数：190)。那 根据其前身(与2000年申请书一起提交)中指出的许多优势领域进行修订， 显然被认为是一个值得注意的进步。然而，尽管总体上评价是积极的， 2002年提案的某些方面不够清楚和/或没有得到充分辩护，导致某些 评论家的担忧和不太“出色”的评级。以下内容将总结在 我们过去的审查、审查人员关注的问题，以及修订后的提案中为解决这些问题而采取的步骤 担忧。 优势(2000/2002年度建议书合计) 1.集中招募参训人员 2.内部评审委员会和同意程序的集中管理 3.与参与者和转介来源保持联系的程序 4.调查人员可使用桌面访问的中央数据库 5.专门培训学员(如模拟扫描仪) 6.纳入行为专家，协助初步培训 7.为实现核心目标提供充足的资源 8.为参赛者提供健康检查 9.跨学科研究评审小组 10.增加应用行为分析员

CLINICAL AND TRANSLATIONAL RESEARCH SUPPORT Kathleen Braden, M.D., Richard W. Serna, Ph.D., & Edward I. Ginns, M.D., Ph.D. Introduction to Revised Proposal This is a revision of a proposal that was submitted with our 2002 application (priority score: 190). That revision built on many areas of strength noted in its predecessor (submitted with the 2000 application), and was apparently judged a noteworthy improvement. Despite a generally positive review, however, aspects of the 2002 proposal were insufficiently clear and/or not adequately defended, leading to certain reviewer concerns and a less-than-"outstanding" rating. What follows will summarize strengths noted in our past reviews, the reviewer concerns, and the steps taken in this revised proposal to address those concerns. Strengths (2000/2002 proposals combined) 1. Centralized participant recruitment 2. Centralized management of IRB and consent procedures 3. Procedures for maintaining contact with participants and referral sources 4. Central database with desktop access for investigators 5. Specialized participant preparation (e.g., mock scanner) 6. Inclusion of behavioral specialist to assist with preliminary training 7. Ample resources for accomplishing the Core's aims 8. Provision of health screen for participants 9. An interdisciplinary research review team 10. Addition of applied behavior analysts