MOUSE CORE FACILITY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 鼠标核心。[玛丽亚·马约雷特·佩涅a，主任]小鼠中心负责监督ApcMin/+小鼠以及转基因和基因敲除小鼠品系的育种种群，提供组织制备和分析方面的帮助，维护组织和载玻片档案，指导研究者护理和使用动物，并培训人员使用所有设备。 此外，该中心还帮助研究人员制定和规划动物方案，以获得南加州大学的批准。的IACUC委员会。 Mouse Core包括一个专用的组织学工作站，用于分析和存储血液数据，以及表征正常组织和肿瘤的大体形态学和详细组织学。 它还包括通过PCR对动物进行基因分型的设备。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Mouse Core. [Maria Marjorette Pe¿a, Director] The Mouse Core oversees breeding stocks of ApcMin/+ mice and of transgenic and knockout mouse lines, provides help with tissue preparation and analysis, maintains an archive of tissues and slides, instructs investigators in the care and use of animals, and trains personnel in use of all equipment. In addition, the Core helps researchers with the development and planning of animal protocols for approval by the USCs IACUC committee. The Mouse Core includes a dedicated Histopathology Workstation for the analysis and storage of blood data, and for characterization of gross morphology and detailed histology of normal tissues and tumors. It also contains equipment for genotyping animals by PCR.