Training Clinical Veterinarians in Nonhuman Primate Clinical Medicine

描述（由申请人提供）：NCRR认识到，在生物医学研究中使用的圈养非人灵长类动物的临床管理方面，训练有素且精通的兽医越来越短缺。我们在这里要求资助三名DVM后居民接受为期两年的灵长类医学培训。维克森林大学医学院（WFUSM）和比较医学部在使用NHP人类疾病模型以及培训实验动物和比较医学兽医方面有50年的历史。这项培训的重点是发展管理、医学、病理学方面的专门知识，以及在生物医学研究中使用国家卫生方案。研究培训补助实验室动物和比较医学培训（MR亚当斯，目前PI）是在其连续资助和NCRR支持的T32赠款的第48个年头。此外，WFUSM目前支持DVM在实验室动物医学和诊断病理学方面的住院医师培训。因此，这里提出的培训是对现有方案的补充，而不是取代现有方案。有16名培训教师，都有比较医学的任命，其中14人是DVM，4人是ACLAM认证，2人是ACVP认证。学员将选择一位DVM导师，他也可以作为有限范围的临床研究项目的顾问，作为他们培训的一部分。所有学员都将有一个ACLAM实习生作为导师或共同导师。培训将包括医学灵长类动物学，生物医学研究中的动物模型，灵长类动物行为和心理健康课程。还包括在灵长类动物临床医学和诊断病理学的轮换;基于经验的IACUC培训;和短期课程在非人类灵长类动物研究资源殖民地的管理：SPF和遗传因素，动物设施的成本核算，和职业健康。学员还将参加每周的期刊俱乐部，临床大圆桌会议和比较病理学会议。最后，到西南生物医学研究基金会实习（获得狒狒的经验和非人灵长类动物种群遗传管理的短期课程）和医学博士。巴斯特罗普的安德森癌症研究中心（对黑猩猩和新热带灵长类动物的经验）也包括在内。

DESCRIPTION (provided by applicant): The NCRR recognizes a growing shortage of veterinarians trained and proficient in the clinical management of captive nonhuman primates used in biomedical research. We request here funding to support three post-DVM residents for two years of training in primate medicine. The Wake Forest University School of Medicine (WFUSM) and the Section of Comparative Medicine have a 50-year history in the use of NHP models of human disease and in the training of veterinarians in laboratory animal and comparative medicine. This training has focused on development of expertise in the management, medicine, pathology and use of NHPs in biomedical research. The research training grant Laboratory Animal and Comparative Medicine Training (MR Adams, current PI) is in its 48th year of continuous funding by and NCRR-supported T32 grant. In addition, WFUSM currently supports residency training of DVMs in laboratory animal medicine and diagnostic pathology. Thus, the training proposed here complements, but does not replace, existing programs. There are 16 members of the training faculty, all have appointments in Comparative Medicine, 14 of these are DVMs, 4 are ACLAM diplomates and 2 are ACVP diplomates. Trainees will choose a DVM mentor, who may also serve as advisor on a limited-scope clinical research project to be conducted as part of their training. All trainees will have an ACLAM diplomate as a mentor or co-mentor. Training will include courses in Medical Primatology, Animal Models in Biomedical Research, and Primate Behavior and Psychological Wellbeing. Also included are rotations in primate clinical medicine and diagnostic pathology; experience-based IACUC training; and short courses in The Management of Nonhuman Primate Research Resource Colonies: SPF and Genetic Considerations, Cost Accounting for Animal Facilities, and Occupational Health. Trainees will also participate in weekly Journal Clubs, Clinical Grand Rounds and the Comparative Pathology Conference. Finally, externships to the Southwest Foundation for Biomedical Research (for experience with baboons and a short course in genetic management of nonhuman primate colonies) and M.D. Anderson Cancer Research Center at Bastrop (for experience with chimpanzees and neotropical primates) are also included.