CORE--ANIMAL

描述（由申请人提供）： 功能：该核心提供一系列服务，这些服务对整体的成功至关重要。 * 肺循环和体循环的体内研究。 * 操作低压舱和高压舱。 * 在柯林斯堡的科罗拉多州立大学的大型动物低压舱中协调动物管理。 * 动物服务的准备和更新。 提供：肺循环和体循环的体内研究：动物核心提供了连接 在离体器官和血管中的体外研究以及在体内环境中的培养细胞。这允许重要的测试的相关性的概念，在减少准备完整的动物。

DESCRIPTION (provided by applicant): Function: This core provides a range of services that are essential to the success of the overall program: * In vivo studies of pulmonary and systematic circulation. * Operation of hypo- and hyperbaric chambers. * Coordination of management of animals in large animal hypobaric chambers at Colorado State University in Fort Collins, CO. * Maintenance of breeding colonies for inbred mice. * Preparation and renewal of animal Services. Provided: In vivo studies of pulmonary and systematic circulation: The Animal Core provides a vital bridge linking in vitro studies in isolated organs and vessels and cultured cells to the in vivo setting. This permits the important test of relevance of concepts developed in reduced preparations to intact animals.