FAMILIAL MELANOMA RESEARCH CLINIC (FMRC)

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 据估计，2000年在美国出生的人中，每75人中就有1人在有生之年患上黑色素瘤。报告显示，8%-12%的黑色素瘤发生在家族群体中，那些与黑色素瘤有一级亲属的人患黑色素瘤的风险被认为增加了2-3倍。 我们已经建立了一个高风险黑色素瘤诊所(家族性黑色素瘤研究诊所，FMRC)，作为一个“核心”设施，为调查具有遗传性黑色素瘤风险的家庭提供一个机制。该诊所仿照先前存在的犹他大学高危乳腺癌和家族性结肠癌诊所的模式，该诊所为遗传性癌症的研究提供了成熟的模型。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is estimated that one out of every 75 people born in the U.S. in the year 2000 will get a melanoma in his/her lifetime. Reports indicate that between 8-12% of melanomas occur within family groups and those people having a first degree relative with melanoma are considered to have a 2-3 fold increased risk of developing melanoma. We have established a high-risk melanoma clinic (Familial Melanoma Research Clinic, FMRC) that acts as a "core" facility to provide a mechanism for investigation of families with an inherited risk of melanoma. This clinic was patterned after the preexisting University of Utah High Risk Breast and Familial Colon Cancer Clinics that provided well-established models for the investigation of inherited cancers.