PREVENTION, CONTROL, AND DISPARITIES (PCD)

预防、控制和差异(PCD)计划的长期目标是研究 基础、流行病学和临床研究的结果已经或应该被传播和应用于 真实的生活。为实现这一目标，将追求以下具体目标：1.控烟--我们的重点 关于通过以下途径减少社区内和个人对烟草的使用和不良影响 使用药理学和行为学方法戒烟，了解戒烟的根本原因 成瘾和吸烟者肺癌筛查研究；2.化学预防/ 致癌-我们对化学预防发展的机制进行体外研究 药物及其在1-3期临床试验中的测试；3.医疗服务不足者的差异--在这方面 目的：我们研究并建议对基于年龄、种族/民族、 收入等；以及4.护理质量/健康结果--我们研究癌症护理的模式和质量， 以及护理方面的变化对结果的影响。 PCD计划由40名成员组成(31名正式成员，5名临床成员，4名准成员) 来自哥伦比亚大学6所学校的15个系，以及威尔·康奈尔大学的教职员工 医学院和长岛大学。该计划由大型计划项目赠款支持， 包括乳腺癌卓越中心拨款，用于研究乳腺癌治疗中的种族差异 以及U54癌症中心/少数族裔服务机构与长岛大学的合作伙伴关系。 在赠款的最后一个预算年度(2006年7月1日至2007年6月30日)，PCD方案总共收到了 1410万美元(直接费用)用于与癌症相关的赠款支助，包括290万美元(直接费用)用于NCI资助，990万美元 (直接成本)其他与癌症相关的同行评审资金，以及130万美元(直接成本)与癌症相关 未经同行审查的资金。自上次提交以来的出版物总数(即2003年-- 目前)为368个，其中11.4%为方案内方案间，33.2%为方案间方案间。 因此，该方案在研究种族/族裔差异以及在生存和健康方面的优势 结果研究，已经变得重要，并与癌症中心的其他项目互动， 包括乳房计划、癌症流行病学计划等。

The long-term goal of the Prevention, Control, and Disparities (PCD) Program is to study how the research findings of basic, epidemiologic, and clinical research have been or should be disseminated and applied in real life. To achieve this end, the following Specific Goals will be pursued: 1. Tobacco control - We focus on the reduction of the use and ill effects of tobacco both within the community and by individuals through the use of pharmacologic and behavioral approaches to smoking cessation, understanding the root causes of addiction, and the study of screening for lung cancer in those who have smoked; 2. Chemoprevention / carcinogenesis - We pursue both in vitro studies of mechanisms for the development of chemopreventive agents and their testing in phase 1-3 clinical trials; 3. Disparities in the medically underserved - In this aim, we study and suggest interventions for disparities in cancer outcomes based on age, race/ethnicity, income, etc.; and 4. Quality of care / health outcomes - We study patterns and quality of cancer care, and the impact of alterations in care on outcomes. The PCD Program consists of 40 members (31 full members, 5 clinical mebers, and 4 associate members) from 15 departments among 6 schools within Columbia University, as well as faculty from the Weill Cornell School of Medicine and Long Island University. The Program is supported by large program project grants, including a Breast Cancer Center of Excellence grant to study racial disparities in breast cancer treatment and a U54 Cancer Center/Minority Serving Institution Collaborative Partnership with Long Island University. For the last budget year of the grant (July 1, 2006 - June 30, 2007), the PCD Program received a total of $14.1M (direct costs) in cancer-relevant grant support, including $2.9M (direct costs) in NCI funding, $9.9M (direct costs) in other cancer-related peer-reviewed funding, and $1.3M (direct costs) in cancer-related non-peer-reviewed funding. The total number of publications since the previous submission (i.e., 2003- present) was 368 of which 11.4% were intra-programmatic and 33.2% inter-programmatic. Thus, the Program's strengths in the study of racial/ethnic disparities, as well as in survivorship and health outcomes research, have become significant and interactive with other programs in the Cancer Center, including the Breast Program, Cancer Epidemiology Program, and others.