TRANSFUSION MEDICINE/HEMOSTASIS TRAIL SITE AT PSBC

描述(由申请人提供) 我们是参与NHLBI赞助的输血医学/止血临床试验网络的全美17个试验点之一。斯利希特博士是血小板剂量试验(PLADO)的首席研究员，这是该网络发起的第一项研究。她曾担任血小板小组委员会主席或联席主席，担任PLADO议定书委员会主席，并参与财务和出版物常设委员会。在这次更新期间，她将参与制定一项评估棕黄色涂层血小板的方案。普莱斯博士是粒细胞输注试验的首席研究员，并担任粒细胞小组委员会主席。这项试验计划于2007年启动。他还参加了TTP小组委员会。格恩斯海默博士一直担任ITP小组委员会主席，最近成为血小板小组委员会主席，并参加了HITT小组委员会。她还将参加新成立的外科出血小组委员会。她是中国邮政储蓄银行负责船舶研究的首席调查员。她已被指定为首席研究员，负责开发评估依西隆-氨基-卡普酸(EACA)作为血小板输注治疗佐剂的试验。(续签申请建议的议定书2)。汤普森博士是血友病小组委员会的成员。在已启动、正在筹备或拟进行的网络试验中，中国邮政储蓄银行正在或计划参与PLADO、SHIP、粒细胞、STAR、HOT、血小板生成素在儿童ITP、FAT和EACA以及血小板输注方面的试验。我们仍在与儿童医院的血友病专家(Dana Matthews博士)合作，以确定她是否愿意让患者参加RICH试验。

DESCRIPTION (provided by applicant) We are one of 17 trial sites across the U.S. that are participating in the NHLBI-sponsored Transfusion Medicine/Hemostasis Clinical Trials Network. Dr. Slichter serves as the lead investigator for the Platelet Dose Trial (PLADO) that was the first study initiated by the Network. She has been Chairman or Co- Chairman of the Platelet Subcommittee, is the Chair of the PLADO Protocol Committee, and participates in the Finance and Publications standing committees. During this renewal, she will participate in the development of a protocol to evaluate buffy-coat platelets. Dr. Price is the lead investigator for the Granulocyte Transfusion Trial and chairs the Granulocyte Sub- committee. This trial is scheduled to be initiated in 2007. He also participates in the TTP Subcommittee. Dr. Gernsheimer has been a Chairman of the ITP Subcommittee, has recently become the Chair of the Platelet Subcommittee, and participates in the HITT Subcommittee. She will also participate in the newly- established Surgical Bleeding Subcommittee. She is PSBC's lead investigator for the SHIP Study. She has been designated as the Principal Investigator to develop the trial to evaluate epsilon-amino-caprioc acid (EACA) as an adjuvent to platelet transfusion therapy. (Renewal application proposed protocol #2). Dr. Thompson participates in the Hemophilia Subcommittee. Of the initiated, in the pipeline, or proposed Network trials, PSBC is participating or plans to participate in the PLADO, SHIP, Granulocyte, STAR, HOT, Thrombopoietin in Childhood ITP, FAT and EACA and platelet transfusion trials. We are still working with the Hemophilia specialist (Dr. Dana Matthews) at our Childrens Hospital to determine if she is willing to enroll patients in the RICH trial.