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中文摘要
翻译
行政、沟通和规划核心的目的是确保协调 Dana Farber/哈佛癌症中心(DF/HCC)骨髓瘤孢子成分并提供监督 以及对孢子的科学、行政和财政方面的领导。孢子主管将会 监督本计划中概述的各种临床和实验室研究的行政协调。 他将在项目内部和项目之间整合科学和临床工作,并确保翻译 化验结果送到床边;反之,从临床开始的化验研究 观察。 在之前的资助期内,基础设施已被创建为具有完美的通信 以及孢子点之间的数据交换,促进合作的临床前研究和临床试验。 多份联合出版物,已完成和正在进行的临床试验,以及几部有针对性的小说的翻译 从工作台到床边的治疗证实了我们努力的沟通和整合。这一核心将 继续促进孢子成员之间以及内部和 外部咨询委员会。它将为拟议的临床试验提供临床研究护理支持。 此外,与前一个资助期一样,临床研究协调员将确保适当的样本 收购和贩运。赠款管理人将以及时和综合的方式分配资源 以协助顺利完成拟议的研究。政府当局的具体目标: 通信和规划核心是为了: 1.监控研究进展和未来规划; 我 2.促进孢子内部和孢子之间的合作研究; 3.将骨髓瘤孢子整合到DF/HCC结构中; 4.提供必要的资源和财政监督;以及 5.促进重大研究成果的快速传播
英文摘要
The purpose of the Administration, Communication, and Planning Core is to assure the coordination of the Dana Farber/Harvard Cancer Center (DF/HCC) Myeloma SPORE components and to provide oversight and leadership of the scientific, administrative, and fiscal aspects of the SPORE. The SPORE Director will oversee the administrative coordination of the various clinical and laboratory studies outlined in this Program. He will integrate scientific and clinical efforts within and between Projects, and assure the translation of laboratory findings to the bedside; and conversely, the initiation of laboratory studies stemming from clinical observations. During the prior funding period, the infrastructure has been created to have seemless communication and exchange of data between SPORE sites, facilitating collaborative preclinical studies and clinical trials. Multiple joint publications, completed and ongoing clinical trials, and the translation of several novel targeted therapies from bench to bedside confirm the communication and integration of our efforts. This Core will continue to facilitate exchange of information among the SPORE members, as well as the internal and external advisory committees. It will provide clinical research nursing support for the proposed clinical trials. In addition, as in the previous funding period, a clinical study coordinator will assure appropriate sample acquisition and trafficking. The grants administrator will allocate resources in a timely and integrated fashion to facilitate successful completion of the proposed studies. The Specific Aims of the Administration, Communication, and Planning Core are to: 1. Monitor research progress and plan for the future; i 2. Foster collaborative research within the SPORE and between SPOREs; 3. Integrate the Myeloma SPORE into the DF/HCC structure; 4. Provide necessary resources and fiscal oversight; and 5. Promote rapid dissemination of significant research finding
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Therapeutically Targeting Plasmacytoid Dendritic Cells in Multiple Myeloma
  • 批准号:
    9153292
  • 项目类别:
  • 资助金额:
    $39.52万
  • 财政年份:
    2016
  • 负责人:
    KENNETH C. ANDERSON
  • 依托单位:
Therapeutically Targeting Plasmacytoid Dendritic Cells in Multiple Myeloma
  • 批准号:
    9518657
  • 项目类别:
  • 资助金额:
    $39.52万
  • 财政年份:
    2016
  • 负责人:
    KENNETH C. ANDERSON
  • 依托单位:
Functional and biologic significance of deacetylase3 inhibition in myeloma
  • 批准号:
    8757662
  • 项目类别:
  • 资助金额:
    $35.33万
  • 财政年份:
    2014
  • 负责人:
    KENNETH C. ANDERSON
  • 依托单位:
Functional and biologic significance of deacetylase3 inhibition in myeloma
  • 批准号:
    9320918
  • 项目类别:
  • 资助金额:
    $35.33万
  • 财政年份:
    2014
  • 负责人:
    KENNETH C. ANDERSON
  • 依托单位:
海外基金