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中文摘要
翻译
贝勒医学院的乳房护理中心是一个基础广泛的多学科组织 由致力于探索乳腺癌生物学的研究人员组成,并通过更好的 了解这种生物学,以提高治愈率和疾病的治疗。的优势所在 中心将补充、加强和扩展NSABP的目标。在过去的五年里,我们 在贝勒医学院建立了临床存在和基础设施,以促进 招募各种各样的患者参加治疗研究。与我们的乳房护理中心一起, 我们是与循道卫理医院合作成立的,并成功地建立了一个 本·陶布综合医院的专门乳腺肿瘤科诊所,这是一家县医院,为 许多患有乳腺癌的弱势和少数族裔妇女,并正在成功地从这个 人口。在过去的25年里,中心的调查人员在 预后和治疗反应预测的分子标志物,以及最近的扩展 他们在高通量基因组技术方面的努力。通过忙碌、高涨的合力 批量临床服务和已建立的临床试验基础设施,与科学家和临床医生一起深入 在翻译和分子标记研究方面经验丰富,我们将能够做出独特的贡献 朝着NSABP为所有乳腺癌女性患者提供最佳、个体化治疗的目标迈进。
英文摘要
The Breast Care Center at Baylor College of Medicine is a broad based, multidiscipiinary organization composed of investigators dedicated to exploring the biology of breast cancer, and through a better understanding of this biology, to improving cure rates and treatments for the disease. The strengths of the Center will complement, reinforce, and extend the goals of the NSABP. Over the past five years, we have established a clinical presence and infrastructure at Baylor College of Medicine which facilitates the recruitment of a wide variety of patients onto treatment studies. Along with our Breast Care Center, established in collaboration with The Methodist Hospital, we have also been successful in establishing a dedicated breast oncology clinic at Ben Taub General Hospital, a county hospital which serves a large number of disadvantaged and minority women with breast cancer, and are successfully recruiting from this population. Center investigators have developed a considerable expertise over the past twenty-five years in molecular markers of prognosis and prediction of response to therapy, and most recently have extended their efforts into high through-put genomic technologies. Through the combined strength of a busy, high volume clinical service and established clinical trial infrastructure, along with scientists and clinicians deeply experienced in translational and molecular marker research, we will be able to make a unique contribution towards the NSABP's goal of optimum, individualized treatment for all women with breast cancer.
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Dual targeting of PI3K and NOS pathways in Metaplastic BreastCancer (MBC)
A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)
A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)
Targeting the Inflammasome As a Treatment Strategy for COVID-19 infected cancer patients
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