UTAH PELVIC FLOOR DISORDERS NETWORK

描述（由申请人提供）：盆底疾病是常见的，麻烦的，并且治疗不充分。来自犹他大学盆底疾病临床中心的研究人员的首要目标是改善盆底功能障碍领域女性的健康状况。为此目的，网站的具体目标包括：1)确定优先研究领域，2)开发评估工具，3)开发和实施PFDN协议，4)招募和招募PFDN协议的受试者，5)实现目标招聘目标和高受试者保留率，6)确保高质量数据，7)准确地将数据传输到数据协调中心，8)参与数据分析，9)向研究界传播结果，10)制作高质量的出版物。本提案中概述的随机临床试验的广泛科学目的是评估盆腔器官脱垂和/或应激性尿失禁手术后盆底肌肉训练是否能改善术后3个月、1年和2年的预后（解剖、症状和生活质量）。

DESCRIPTION (provided by applicant): Pelvic floor disorders are common, bothersome, and inadequately treated. The overarching aim of the investigators from the proposed University of Utah Pelvic Floor Disorders Clinical Site is to improve women's health in the area of pelvic floor dysfunction. To this end, site specific aims include: 1) Identifying priority areas of research, 2) Developing assessment tools, 3) Developing and implementing PFDN protocols, 4) Recruiting and enrolling subjects in PFDN protocols, 5) Achieving on-target recruitment goals and high subject retention, 6) Ensuring high-quality data, 7) Transmitting data accurately to the Data Coordinating Center, 8) Participating in data analysis, 9) Disseminating results to the research community, and 10) Producing high-quality publications. The broad scientific aim for the randomized clinical trial outlined in this proposal is to evaluate whether post- operative pelvic floor muscle training following surgery for pelvic organ prolapse and/or stress urinary incontinence improves post-operative outcomes (anatomic, symptomatic and quality of life outcomes) at 3 months, 1 year and 2 years post-operatively.