South Texas Pediatric Minority Based CCOP

描述（由申请人提供）：南德克萨斯州儿科少数民族社区临床肿瘤学项目（STP-MB-CCOP）的长期目标是降低居住在服务区的墨西哥裔美国人（MA;此处与西班牙裔同义）儿童和青少年的癌症发病率、发病率和死亡率。 STP-MB-CCOP的四个具体目标是：1）为服务于南德克萨斯州地理区域的儿科肿瘤提供者提供全面、综合的数据管理服务; 2）为儿科肿瘤学家、数据管理和支持人员提供旅行支持，以便在医疗服务不足的地区外展诊所; 3）提供一个集中的西班牙语翻译系统，对服务区的墨西哥裔美国人具有文化敏感性; 4）制定与服务区的墨西哥裔美国人有关的地方癌症控制试点计划。研究计划涉及圣安东尼奥临床研究办公室的运作，该办公室协调组成机构的数据管理活动，包括主要数据收集和提交、IRB批准、西班牙语翻译、研究基地稽查和样本采集。它将使用信息学数据交换和获取系统，这是一个以网络为基础的系统，所有STP-MB-CCOP中心，无论其位于何处，都可以进入该系统。将在边境各州开展各级外联活动（教育、常驻儿科肿瘤学家的数据管理支持和外联诊所），使患有癌症的儿童和青少年能够参加临床试验。知情同意书和教育材料的集中西班牙语翻译将确保所有患者和家属都能以自己的语言收到信息，从而对治疗依从性产生积极影响。STP-MB-CCOP正试图通过制定与墨西哥裔美国人相关的当地癌症控制倡议并扩展到其他COG CCOP机构，来弥补儿科癌症控制和预防试验的不足。 该方案有一个正在进行的评价方案，包括机构主要研究人员及其CRA之间的每周会议、行政执行委员会的每月会议和由所有STP-MB-CCOP成员参加的季度会议，以审查联合体活动。

DESCRIPTION (provided by applicant): The long-term goal of the South Texas Pediatric Minority-Based Community Clinical Oncology Program (STP-MB-CCOP) is to reduce the incidence, morbidity and mortality of cancer among Mexican-American (MA; herein used synonymously with Hispanic) children and adolescents residing in the service area. The four specific aims of the STP-MB-CCOP are: 1) Provide comprehensive, integrated data management services accessible to pediatric oncology providers serving the geographic region known as South Texas; 2) Provide travel support for pediatric oncologists, data management and support personnel to outreach clinics within the medically under served areas; 3) Provide a centralized Spanish translation system culturally sensitive to the Mexican-American population in the service area; and 4) Develop local cancer control pilot initiatives relevant to the Mexican-American population in the service area. The research plan involves the operation of a Clinical Research Office in San Antonio that coordinates the data management activities of the component institutions, including primary data collection and submission, IRB approval, Spanish translation, research base audits and sample collection. It will use the Informatics Data Exchange and Acquisition System (IDEAS) a Web based system that can be accessed by all STP-MB-CCOP centers regardless of their location. Outreach activities at all level (education, data management support of resident pediatric oncologist and outreach clinics) will be provided in border counties to allow children and adolescents with cancer to have access to clinical trials. Centralized Spanish translation of consent forms and educational materials will assure that all patients and family receives information in their own language with a resulting positive impact on compliance with treatment. STP-MB-CCOP is attempting to remedy the paucity of pediatric cancer control and preventive trials by developing local cancer control initiatives pertinent to the Mexican-American population and expandable to other COG CCOP institutions. The program has an ongoing evaluation program involving weekly meetings between institution PIs and their CRAs, monthly meeting of the Administrative Executive Committee and quarterly meeting involving all STP-MB-CCOP members to review the consortium activities.