Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth

描述（由申请人提供）： Jaimie Davis获得了德克萨斯大学奥斯汀分校的营养科学博士学位，并在南加州大学预防医学系担任博士后研究员两年多。戴维斯博士的近期职业目标是1）接受进一步培训，成为一名独立的调查员，以竞争同行评审的资金，特别是R 01赠款; 2）获得运动生理学各个方面的知识，包括运动干预的设计和实施，以及运动测试和解释; 3）接受关于如何使用，整合和评分动机访谈的进一步培训，以促进身体活动行为的改善; 4）调查运动干预降低代谢危险因素的机制; 5）教育和指导本科生和研究生，使他们为预防和治疗儿童肥胖和2型糖尿病的职业做好准备。我的总体长期职业目标是开发和实施新颖，有效和可持续的干预措施，这些干预措施可以在高风险的少数群体社区环境中进行翻译和交付。我的培训活动将包括：1）直接指导Michael Goran、Leslie伯恩斯坦、Donna Spruijt-梅斯和托德施罗德，并与Kathryn Schmitz和Teresa Moyer合作; 2）参加培训会议和研讨会，以获得完成本研究所需的技能和知识; 3）在南加州大学参加正式课程，以更好地了解运动生理学、脂肪分布和行为理论。拟议的研究项目的总体目标是检查16周的循环训练（力量训练+有氧活动）计划的影响，有和没有行为组件利用动机访谈，在45超重的拉丁裔少女（14-18岁）减少肥胖和2型糖尿病的危险因素。该16周随机对照研究将检查以下3个干预组对胰岛素动力学、脂肪组成和分布以及习惯性和随意性体力活动的增量效应：1）对照组（延迟干预），2）巡回训练组（每周2次）或3）巡回训练+动机性访谈组（每周2次CT +每周MI会话）。受试者将接受临床测试以评估代谢和生理结局，并接受直接观察以评估干预前后的随意体力活动。 本案无关这项研究将开发和实施一个独特的电路训练（力量训练+心血管运动）计划，有和没有动机访谈行为组成部分，超重的拉丁裔青少年女性，旨在减少肥胖和2型糖尿病的危险因素。这项研究的结果将有助于在社区环境中建立更广泛，多成分和持续的干预措施，以减少高风险少数民族社区的肥胖和代谢疾病。

DESCRIPTION (provided by applicant): Jaimie Davis received her doctorate in Nutritional Sciences from the University of Texas at Austin and has worked as a Postdoctoral Fellow for just over 2 years in the Department of Preventive Medicine at the University of Southern California. Dr. Davis's immediate career goals are to 1) receive further training to become an independent investigator to compete for peer reviewed funding, specifically R01 grants; 2) gain knowledge in various aspects of exercise physiology including the design and implementation of exercise interventions, and exercise testing and interpretation; 3) receive further training on how to use, integrate, and score Motivational Interviewing to foster improvements in physical activity behaviors; 4) investigate mechanisms that decrease metabolic risk factors with exercise interventions; and 5) educate and mentor undergraduate and graduate students in preparing them for careers in prevention and treatment of childhood obesity and type 2 diabetes. My overall long-term career goal is to develop and implement novel, effective and sustainable interventions that can be translated and delivered in high-risk minority, community settings. My training activities will involve: 1) direct mentorship of Michael Goran, Leslie Bernstein, Donna Spruijt- Metz, and Todd Schroeder and collaboration with Kathryn Schmitz and Teresa Moyer; 2) attending training conferences and seminars to gain the skills and knowledge needed to complete this study; and 3) formal coursework at USC to better understand exercise physiology, fat distribution and behavioral theories. The overall goal of the proposed research project is to examine the effects of a 16-week circuit-training (strength training + aerobic activities) program, with and without a behavioral component utilizing motivational interviewing, on decreasing obesity and type 2 diabetes risk factors in 45 overweight Latina adolescent girls (14-18 years of age). This 16-week randomized control study will examine the incremental effects of the following 3 intervention groups on insulin dynamics, fat composition and distribution, and habitual and ad libitum physical activity: 1) Control group (delayed intervention), 2) Circuit training group (2 times per week), or 3) Circuit training + Motivational Interviewing group (2 times per week of CT + weekly Ml sessions). Subjects will undergo clinical testing to assess metabolic and physiological outcomes and undergo direct observations to assess ad libitum physical activity before and after intervention. Relevance. This study will develop and implement a unique circuit training (strength training + cardiovascular exercise) program, with and without a motivational interviewing behavioral component, for overweight Latina adolescent females designed to reduce obesity and type 2 diabetes risk factors. Findings from this study will help create more wide scale, multi-component, and sustaining interventions in community settings targeting obesity and metabolic disease reduction in high-risk minority communities.