SURFACTANT POSITIVE AIRWAY PRESSURE AND PULSE OXIMETRY TRIAL IN ELBW INFANTS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 研究人员希望确定是否可以通过使用持续正压通气（CPAP）和允许通气策略而不是自动气管内插管，表面活性剂给药和传统的机械通气来降低早产儿支气管肺发育不良（BPD）的发生率。 他们还希望确定这些婴儿保持较低的氧饱和度是否会降低早产儿视网膜病变（ROP）的发生率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The investigators hope to determine if the incidence bronchopulmonary dysplasia (BPD) can be reduced in premature infants by using continuous positive air pressure (CPAP) and a permissive ventilation strategy rather than automatic endotracheal intubation, surfactant administration, and conventional mechanical ventilation beginning in the delivery room. They also hope to determine if maintaining a lower oxygen saturation in these infants will reduce the incidence of significant retinopathy of prematurity (ROP).