ADOLESCENT MASTER PROTOCOL (AMP) - IMPACT OF HIV AND ART ON GROWTH

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 确定HIV感染和ART对青春期前和围产期HIV感染的青少年从青春期进入成年期时的生长和青春期发育（及其激素调节）沿着认知、学术和社会发展的影响。 确定艾滋病的感染性和非感染性并发症，并评估其与抗逆转录病毒疗法的关系。 调查： 糖代谢、身体组成和骨矿化的变化; 脂代谢改变及其他心血管疾病危险因素; 认知和行为随时间的变化; 艾滋病毒二次传播的危险因素; 女性宫颈HPV感染的发生率和临床病程

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To define the impact of HIV infection and ART on growth and pubertal development (and their hormonal regulation) along with the cognitive, academic, and social development, of pre-adolescents and adolescents with perinatal HIV infection as they move through adolescence into adulthood. To identify infectious and non-infectious complications of HIV disease and evaluate their associations with ART. Investigate: Changes in glucose metabolism, body composition and bone mineralization; Changes in lipid metabolism and other risk factors for cardiovascular disease; Cognitive and behavioral changes over time; Risk factors for secondary transmission of HIV; Occurence and clinical course of cervical HPV infections among females.