NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) DATABASE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这是一项多中心观察性III期研究，每个研究中心有200例确诊或疑似非酒精性脂肪性肝病（NAFLD）或隐源性肝硬化患者。这项研究的目的是：a）研究NAFLD的病因学、自然史、诊断、治疗和预防，B）开发包括从NAFLD患者获得的肝组织、血清、血浆、DNA和细胞系的样本库，和c）提供用于NAFLD的发病机理、自然史和治疗的辅助研究的资源。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a multi-center observational phase 3 study of 200 patients per site with definite or suspected nonalcoholic fatty liver disease (NAFLD) or cryptogenic cirrhosis. This study will aim to: a) investigate the etiology, natural history, diagnosis, treatment and prevention of NAFLD, b) develop a specimen bank comprising liver tissue, serum, plasma, DNA, and cell lines obtained from NAFLD patients and c) provide a resource for ancillary studies of the pathogenesis, natural history, and treatment of NAFLD.