PREDICTIVE MEDICINE RESEARCH: INVESTIGATION OF HEALTH, SUB-CLINICAL ORGAN SYS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的主要目的是为各种生理和心理因素建立标准值，这些因素可能赋予疾病易感性和复原力。这项研究的次要目标是评估推定标记物的试验内和时间稳定性，以及在推定健康的人群中，评估器官系统疾病的亚临床测量是否与这些新的风险标记物相关。为了实现这些目标，一大批多学科的调查人员提议对288名年龄在30岁到90岁之间、表面上看起来健康的成年人进行一系列因素的评估(按性别、种族和年龄按十年进行平衡)。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overarching aim of this study is to establish normative values for a wide variety of physiological and psychological factors that likely confer susceptibility to disease as well as resiliency. Secondary goals of the proposed study are to evaluate intra-assay and temporal stability of putative markers, as well as evaluate whether sub clinical measures of organ-system disease correlate with these novel risk markers in a putatively healthy population. To accomplish these aims, a large group of multi-disciplinary investigators propose to evaluate a slough of factors in 288 apparently healthy adults between the ages of 30 and 90 years (balanced for sex, ethnicity and age by decade).