7th International Conference on Frontotemporal Dementias

描述（由申请人提供）：自1986年在瑞典隆德举行的第一届额颞叶痴呆（FTD）国际会议以来，将参与FTD领域研究的科学家聚集在一起的活动和兴趣日益增加。这些会议的一个特点是其多学科性，这使得具有不同技术专长领域的科学家能够迅速扩大知识和传播思想。在同一时期，分子遗传学的快速发展和人类基因组计划的完成使FTD研究的进展比前100年快得多。在过去的二十年里，对痴呆症分子基础的研究已经导致了对阿尔茨海默病和许多其他痴呆症的临床和神经病理学基础的理解。阿尔茨海默病和其他退行性痴呆之间的差异有时很难在临床上检测到;然而，成像，遗传和其他生物标志物研究的日益复杂导致了这些疾病的新分类。1994年发现FTD与17号染色体的连锁，这是一个主要的推动力，并导致重新努力了解皮克病和其他形式的额颞叶痴呆症的生物学基础（9）。额颞叶痴呆，最近被称为额颞叶变性（FTLD），是一组临床，病理和遗传多样性疾病，共同构成了65岁以下人群中痴呆的第二大常见原因。具体目标：1）支持学费和旅费津贴的初级教师谁被邀请发言，2）支持学费和旅费津贴的少数民族学生，教师或其他专业卫生保健工作者谁提交了一个摘要的海报演示文稿，和3）支持学费和旅费津贴的少数民族非专业照顾者照顾受影响的家庭成员。已经成立了四个不同的委员会，以协助筹备这次会议的各个方面。科学和护理委员会的成员包括当今FTD领域的许多领先研究人员。会议计划旨在为与会者提供一个了解与FTD相关的广泛主题的机会。这次会议的一个主要重点是纳入初级调查人员和少数民族和服务不足的人口。本申请寻求资金，以帮助主要研究人员在这一目标。 公共卫生相关性：本申请的目的是请求资金支持第七届额颞叶痴呆症国际会议。本次会议是研究科学家，临床医生和其他医疗保健专业人员分享他们每个学科的最新信息的论坛。除了强调在各个研究领域取得的进展外，本次会议还将为非专业护理人员提供一个接触新知识并与研究人员和其他护理人员互动的机会。

DESCRIPTION (provided by applicant): Since the first international conference on frontotemporal dementias (FTD), which took place in Lund, Sweden in 1986, there has been increasing activity and interest in bringing together scientists involved in research in the field of FTD. A characteristic of these conferences has been their multidisciplinarity, which has allowed a rapid expansion of knowledge and dissemination of ideas among scientists with different areas of technical expertise. During the same period of time, the rapid developments in molecular genetics and the completion of the human genome project have allowed FTD research to progress much more rapidly than in the preceding 100 years. Over the past two decades, studies of the molecular basis of dementia have led to an understanding of the clinical and neuropathologic basis of Alzheimer disease and of numerous other dementias. The difference between Alzheimer disease and other degenerative dementias is, at times, difficult to detect clinically; however, the increased sophistication of imaging, genetic and other biomarker studies has led to the new classifications of these disorders. A major impetus occurred in 1994, with the discovery of a linkage of FTD to chromosome 17, and has led to a renewed effort to understand the biological basis of Pick disease and other forms of frontotemporal dementia (9). Frontotemporal dementia, more recently called frontotemporal lobar degeneration (FTLD), is a clinically, pathologically and genetically diverse group of disorders that together constitute the second most common cause of dementia in those younger than 65 years of age. Specific Aims: 1) Support tuition and travel stipends for junior faculty who have been invited to speak, 2) Support tuition and travel stipends for minority students, faculty or other professional health care workers who have submitted an abstract for a poster presentation, and 3) Support tuition and travel stipends for minority non-professional caregivers caring for an affected family member. Four different committees have been formed to aid in the various aspects of preparing for this conference. The scientific and caregiver committees' membership includes many of the leading researchers in the field of FTD today. The conference programs have been designed to offer attendees an opportunity to learn about a broad spectrum of topics related to FTD. A major point of emphasis for this conference is the inclusion of junior investigators and minorities and under-served populations. This application seeks funds to aid the principal investigator in this goal. PUBLIC HEALTH RELEVANCE: The purpose of this application is to request funds to support the 7th International Conference on Frontotemporal Dementias. This conference is a forum for research scientists, clinicians, and other health care professionals to share the latest information from each of their disciplines. In addition to highlighting the progress made in the various areas of research, this conference will provide an opportunity for non-professional caregivers to be exposed to new knowledge and to interact with researchers and other caregivers.