Endocrine Scientists Training Program

描述（由申请人提供）：内分泌学和代谢紊乱在美国很普遍。要解决这些难题，不仅需要培养大量的医生来照顾受影响的患者，还需要培训熟练的研究人员来开发创新的治疗方法和预防措施，并深入研究疾病的基本机制。印第安纳大学医学院在许多医学领域都处于领先地位。它的儿科内分泌科和医学系的内分泌与代谢科都是备受尊敬的大型研究部门，长期以来一直在指导博士后和博士生，包括在儿科和成人内分泌学的研究领域相互培训研究员。这里描述的内分泌科学家培训计划为儿科、成人或综合医学-儿科内分泌学培训的年轻科学家提供了机会，以提高他们在基础实验室、临床或转化研究方面的技能，从而成为独立的学术研究人员。在完成住院医师培训后，高素质的医生进入内科、儿科内分泌学或联合医学-儿科内分泌学奖学金，接受各自学科的临床培训，然后进入内分泌学基础科学轨道或内分泌学临床研究轨道两个轨道之一的联合项目。这些轨道提供广泛的直接和教学研究培训。内分泌学基础科学课程需要一系列研究生水平的课程，包括分子生物学、生物统计学和研究伦理学的研究。内分泌临床研究跟踪学员通过k30资助的CITE项目获得临床研究理学硕士学位。参加内分泌科学家培训计划的学员将获得为期两年的培训支持。在之前的项目期间，该项目培养了五位内分泌领域的顶尖内科科学家。这个项目的毕业生都在主要医学院担任学术职务，我们期待他们将继续从事尖端研究，为美国人民的健康做出重大贡献。相关性（见说明）：2型糖尿病的爆发和相关的内分泌和代谢问题正在造成巨大的公共卫生损失。阐明疾病机制和开发新的治疗方法对于解决这些问题至关重要。要做到这一点，只能通过培养一批关键的年轻研究人员来发展和推进解决这些问题的努力。

DESCRIPTION (provided by applicant): Disorders of endocrinology and metabolism are prevalent in the U.S. Addressing these difficult dilemmas requires not only the development of a critical mass of physicians to care for affected patients, but also the training of skilled researchers to develop innovative therapies and preventive measures and to delve into the basic mechanisms of diseases. The Indiana University School of Medicine is a leader in many fields of medicine. Its Section of Pediatric Endocrinology and the Division of Endocrinology and Metabolism in the Department of Medicine are both large well respected research divisions with long histories of mentoring pre-and postdoctoral trainees, including training one another's fellows in research that spans the spectrum of pediatric and adult Endocrinology. The Endocrine Scientist Training Program described here provides the opportunity for young scientists in Pediatric, Adult, or Combined Medicine-Pediatric Endocrinology training to enhance their skills in either basic laboratory, clinical, or translational research, leading to careers as independent academic researchers. After completion of their residency training, highly qualified physicians enter either the Internal Medicine, Pediatric Endocrinology, or combined Medicine- Pediatric Endocrinology fellowship, receive clinical training in the respective discipline[s), then enter this combined program in one of two tracks, the Basic Science of Endocrinology Track or the Endocrinology Clinical Research Track. These tracks provide extensive direct and didactic research training. The Basic Science of Endocrinology Track requires a series of graduate level courses, including studies in Molecular Biology, Biostatistics, and Research Ethics. The Endocrinology Clinical Research Track trainees obtain a Masters of Science in Clinical Research through our K30-funded CITE program. Trainees in the Endocrine Scientist Training Program receive two years of support for their training. Over the previous project period, this program has trained five top-notch physician scientists in the field of Endocrinology. The graduates of this program all have academic positions at major medical schools, and we anticipate that they will continu to engage in cutting-edge research to make major contributions to the health of the American people. RELEVANCE (See instructions): The eruption of type 2 diabetes and related endocrine and metabolic problems is taking a tremendous public health toll. The elucidation of disease mechanisms and the development of new treatments for these and related conditions is critical to address these issues. This can only be done by training a critical mass of young researchers to develop and carry forward the efforts to solve these problems.