Training in Pediatric Endocrinology and Diabetes Research

该提案寻求继续支持耶鲁大学的儿科内分泌学/糖尿病研究培训 程序。申请寻求增加目前的资助水平(从2名博士后增加到3名博士后 津贴)。申请是基于我们的培训计划和导师的记录；延期 包括内分泌研究的所有领域；我们的临床、基础和 翻译研究计划；我们的一些受训人员需要延长的培训期限，以 获得博士学位和儿科内分泌学和内分泌学方面持续严重短缺的内科科学家 糖尿病研究。耶鲁大学有一系列令人印象深刻的资源来支持这个项目，包括 耶鲁大学儿童健康研究中心、磁共振研究中心、JDRF 低血糖研究中心，耶鲁大学肌肉骨骼疾病核心中心， X-连锁低磷血症，人类和翻译免疫学的新计划，最近， 由CTSA支持的耶鲁临床研究中心已经改变了为 该机构的临床和转化性研究。我们的许多培训教员(即坦博兰、 卡彭特、里夫基斯、舍温、舒尔曼、赫罗德和罗斯曼)在所有这些方面都扮演着重要的领导角色 资源。项目主任和培训人员都是备受尊敬和富有成效的调查人员， 广泛的同行评审赠款支持，以资助学员的项目，他们有出色的记录 在培训博士后研究员方面。博士后实习生可以在五个主要研究领域中选择 培训包括1)T1 DM技术和治疗，2)自身免疫和(T1 DM的3-细胞保存，3) 儿童肥胖与2型糖尿病；4)骨生物学与疾病；5)发育生物学。我们的核心产品之一 教育活动是调查医学计划(IMP)，它提供了严格的课程 必修课和选修课沿着两条途径进行，即以病人为中心和以疾病为中心。成功 完成课程工作和论文项目将允许受训者获得通过 医学部。IMP课程面向非博士生。我们的核心是 少数族裔招聘的努力是我们与莫尔豪斯医学院儿科的关系 为学生和住院医生提供暑期奖学金的医学。

This proposal seeks continued support for the Yale Training in Pediatric Endocrinology/Diabetes Research Program. The application seeks an increase in the current level of funding (from 2 to 3 post-doctoral stipends per year).The request is based on the track record of our training program and mentors; extension of the program to include all areas of endocrine research; the quality and diversity of our clinical, basic and translational research programs; the extended period of training that is required for some of our trainees to obtain a PhD degree and the continuing dire shortage of physician-scientists in pediatric endocrinology and diabetes research. Yale has an impressive array of resources that support this program, including the DERC, the Yale Child Health Research Center, the Magnetic Resonance Research Center, the JDRF Center for the Study of Hypoglycemia, the Yale Core Center for Muscular Skeletal Diseases, the Center for X-linked Hypophosphatemia, the new program in Human and Translational Immunology and, most recently, the CTSA-supported Yale Center for Clinical Investigation that has transformed the support provided for clinical and translational research at this institution. Many of our training faculty (i.e., Tamborlane, Carpenter, Rivkees, Sherwin, Shulman, Herold and Rothman) have major leadership roles in all of these resources. The Program Directors and training faculty are highly respected and productive investigators with extensive peer-reviewed grant support to fund trainees' projects and they have an outstanding track record in training post-doctoral fellows. Post-doctoral trainees can choose between five major areas of research training including 1) T1DM technology & therapeutics, 2) autoimmunity & (3-cell preservation in T1DM, 3) childhood obesity & T2DM, 4) bone biology & disease and 5) developmental biology. A centerpiece of our educational activities is the Investigative Medicine Program (IMP) that provides a rigorous curriculum of required and elective courses along two pathways, i.e. patient-oriented and disease-oriented. Successful completion of course work and thesis project will allow trainees to receive a Ph.D. that is awarded through the Department of Medicine. IMP courses are available for non Ph.D. candidates. The centerpiece of our minority recruitment efforts is our relationship with the Department of Pediatrics at Morehouse School of Medicine that offers summer fellowships to their students and residents.