ShEEP Request for a Kubtec XPERT 80 Shielded Cabinet X-ray System

此申请的目的是获得资金购买Kubtec XPERT 80屏蔽柜X射线 系统可供不同研究学科（包括神经、肌肉和骨骼）的多名研究者使用 生物学，统称为神经肌肉骨骼生物学，在理查德L。Roudebush VA医疗中心 (RLR VAMC）在印第安纳波利斯。神经肌肉骨骼疾病是高度VA相关的医学问题， 迫切的医疗需求。在印第安纳波利斯的RLR VAMC，强有力的互动和合作 在多名具有神经肌肉骨骼疾病专业知识的研究者中建立。与 购买XPERT 80屏蔽柜X射线系统，该系统可供不同的VA调查人员使用 学科，可以进一步加强这种合作。XPERT 80屏蔽柜X射线系统， 我们要求将高对比度数字探测器与用户友好的图像分析软件工具相结合， 可以测量图像以精确地获得感兴趣的信息， 在关节处或骨髓腔内、骨愈合、植入物放置的精确性等。在该应用中， 提出了两个具体目标。在目标1中，我们描述了Kubtec的采购和维护计划 XPERT 80屏蔽柜X射线系统，供专门的VA研究人员使用。我们已获得报价单 关于KUB Technologies Inc.用于XPERT 80屏蔽柜X射线系统。我们进一步讨论 XPERT 80屏蔽柜X射线系统的管理计划。在目标2中，我们讨论了 科学的质量和促进专门的VA研究人员之间的合作。过程中 在过去的8年里，我们已经建立了一个强大的和动态的神经肌肉骨骼研究计划（NMS）， 研究与开发服务。XPERT 80屏蔽柜X射线系统代表了最先进的X射线技术， 射线和图像分析技术，可用于许多神经，肌肉，骨骼和癌症- 相关项目。因此，该系统的潜在采购将提高目前的成像能力， 我们的核心设施，并允许扩大合作VA相关的研究项目。目前没有X- X射线系统与XPERT 80屏蔽柜X射线系统在VA或任何地方的能力 印第安纳州大学医学院（IUSM）校园。我们收购XPERT的总体目标是 80屏蔽柜X射线系统是在RLR VAMC创造新的合作，导致创新 解决退伍军人面临的健康问题。为了达到我们的目标，我们组建了一个16人的团队 研究人员，被任命为研究科学家，研究职业科学家，高级研究职业 科学家，甚至新的有前途的调查人员与无报酬任命（WOC）。具有该 最先进X射线系统肯定会为RLR VAMC的研究和合作开辟新途径 如果没有它，这是不可能的。

The purpose of this application is to secure funding to purchase a Kubtec XPERT 80 shielded cabinet X-ray system for use by multiple investigators with different research disciplines including neural, muscle, and bone biology, collectively called neuromusculoskeletal biology, at the Richard L. Roudebush VA Medical Center (RLR VAMC) at Indianapolis. Neuromusculoskeletal disorders are highly VA-related medical problems, and are urgently unmet medical needs. At the RLR VAMC in Indianapolis, strong interactions and collaborations have been established among multiple investigators with expertise in neuromusculoskeletal disorders. With the purchase of the XPERT 80 shielded cabinet X-ray system, which can be used by VA investigators of different disciplines, such collaborations could be further enhanced. The XPERT 80 shielded cabinet X-ray system that we request combines high contrast digital detectors with user-friendly image analysis software tools to provide images which can be measured to precisely obtain information of interest such as bone resorption/degradation at the joint or within the marrow cavity, bone healing, precision of implant placement, etc. In this application, two specific aims are proposed. In Aim 1, we describe the purchase and maintenance plan of the Kubtec XPERT 80 shielded cabinet X-ray system for use by dedicated VA researchers. We have obtained a quotation from KUB Technologies Inc. for the XPERT 80 shielded cabinet X-ray system. We further discuss the management plan of the XPERT 80 shielded cabinet X-ray system. In Aim 2, we discuss the enhancement of the quality of science and promotion of collaboration among dedicated VA researchers. Over the course of the past 8 years, we have established a strong and dynamic Neuromusculoskeletal research program (NMS) in the Research & Development Service. The XPERT 80 shielded cabinet X-ray system represents state-of-the art X- ray and image analysis technology that can be used for a number of neural, muscular, skeletal, and cancer- related projects. As such, potential acquisition of this system would enhance the current imaging capabilities of our core facilities and allow expansion of collaborative VA-related research projects. There is currently no X- ray system with the capabilities of the XPERT 80 shielded cabinet X-ray system at the VA or anywhere on the Indiana University School of Medicine (IUSM) campus. Our overall objective with the acquisition of the XPERT 80 shielded cabinet X-ray system is to create new collaborations at RLR VAMC that lead to innovative solutions for health problems facing our veterans. To reach our goal, we have formed a team of 16 investigators, with appointments as Research Scientists, Research Career Scientists, Senior Research Career Scientist, and even new promising investigators with Without Compensation appointments (WOC). Having this state-of-the-art X-ray system will certainly open up new avenues of research and collaboration at RLR VAMC that would not be possible without it.